1 to 10 of 43 literature results

• RNase H-mediated retrovirus destruction in vivo triggered by oligodeoxynucleotides.

  The HIV-1 RNase H can be prematurely activated by oligodeoxynucleotides targeting the highly conserved polypurine tract required for second strand DNA…

  Authors: Kathrin Matzen, Lina Elzaouk, Alexey A Matskevich, Anja Nitzsche, Jochen Heinrich, Karin Moelling

  Source: Nature biotechnology. 2007 Jun

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• Regulation of epithelial wound closure and intercellular adhesion by interaction of AF6 with actin cytoskeleton.

  AF6 is a human multi-domain protein involved in signaling and organization of cell junctions during embryogenesis. Its homologue in rat is called afad…

  Authors: Mihaela Lorger, Karin Moelling

  Source: Journal of cell science. 2006 Aug 15

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• c-Src-mediated epithelial cell migration and invasion regulated by PDZ binding site.

  c-Src tyrosine kinase controls proliferation, cell adhesion, and cell migration and is highly regulated. A novel regulatory mechanism to control c-Src…

  Authors: Martin Baumgartner, Gerald Radziwill, Mihaela Lorger, Andreas Weiss, Karin Moelling

  Source: Molecular and cellular biology. 2008 Jan

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• Bcr is a negative regulator of the Wnt signalling pathway.

  The Wnt signalling pathway can activate transcription of genes such as c-myc through beta-catenin. Here, we describe the protein breakpoint cluster re…

  Authors: Angelika Ress, Karin Moelling

  Source: EMBO reports. 2005 Nov

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• The PDZ protein MPP2 interacts with c-Src in epithelial cells.

  c-Src is a non-receptor tyrosine kinase involved in regulating cell proliferation, cell migration and cell invasion and is tightly controlled by rever…

  Authors: Martin Baumgartner, Andreas Weiss, Thorsten Fritzius, Jochen Heinrich, Karin Moelling

  Source: Experimental cell research. 2009 Oct 15

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• Heteromeric complex formation of ASK2 and ASK1 regulates stress-induced signaling.

  Apoptosis signal-regulating kinase 2 (ASK2) is an interaction partner of the highly related ASK1. Here, we describe a regulatory function of ASK2 in s…

  Authors: Elisabeth Ortner, Karin Moelling

  Source: Biochemical and biophysical research communications. 2007 Oct 19

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• Analysis of antitumor activity elicited by vaccination with combinations of interleukin-12 DNA with gp100 DNA or the chemokine CCL21 in vivo.

  The antitumor efficacy of human melanoma-associated antigen (hgp100) and chemokine CCL21 in combination with interleukin-12 (IL-12) was evaluated in a…

  Authors: Lina Elzaouk, Jovan Pavlovic, Karin Moelling

  Source: Human gene therapy. 2006 Aug

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• Bcr interferes with beta-catenin-Tcf1 interaction.

  The beta-catenin/Tcf complex is a downstream effector of the Wnt signalling pathway. It is a transcription complex, which activates gene expression an…

  Authors: Angelika Ress, Karin Moelling

  Source: FEBS letters. 2006 Feb 20

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• RIP2 mediates LPS-induced p38 and IkappaBalpha signaling including IL-12 p40 expression in human monocyte-derived dendritic cells.

  IL-12, the critical factor for the generation of the Th1 type immune response, is produced by dendritic cells (DC) upon stimulation with LPS. Differen…

  Authors: Nurguel Usluoglu, Jovan Pavlovic, Karin Moelling, Gerald Radziwill

  Source: European journal of immunology. 2007 Aug

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• Retroviral self-inactivation in the mouse vagina induced by short DNA.

  Human immunodeficiency virus (HIV) has been shown to undergo self-destruction upon treatment of cell-free virions with partially double-stranded oligo…

  Authors: Lina Wittmer-Elzaouk, Jiunshan Jung-Shiu, Jochen Heinrich, Karin Moelling

  Source: Antiviral research. 2009 Apr

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