1 to 8 of 8 literature results

• A pluripotency signature predicts histologic transformation and influences survival in follicular lymphoma patients.

  Histologic transformation (HT) of follicular lymphoma to diffuse large B-cell lymphoma (DLBCL-t) is associated with accelerated disease course and dra…

  Authors: Andrew J Gentles, Ash A Alizadeh, Su-In Lee, June H Myklebust, Catherine M Shachaf, Babak Shahbaba, Ronald Levy, Daphne Koller, Sylvia K Plevritis

  Source: Blood. 2009 Oct 8

  View Full Text

• Therapeutic effect of CD137 immunomodulation in lymphoma and its enhancement by Treg depletion.

  Despite the success of passive immunotherapy with monoclonal antibodies (mAbs), many lymphoma patients eventually relapse. Induction of an adaptive im…

  Authors: Roch Houot, Matthew J Goldstein, Holbrook E Kohrt, June H Myklebust, Ash A Alizadeh, Jack T Lin, Jonathan M Irish, James A Torchia, Arne Kolstad, Lieping Chen,…

  Source: Blood. 2009 Oct 15

  View Full Text

• CD81 protein is expressed at high levels in normal germinal center B cells and in subtypes of human lymphomas.

  CD81 is a tetraspanin cell surface protein that regulates CD19 expression in B lymphocytes and enables hepatitis C virus infection of human cells. Imm…

  Authors: Robert F Luo, Shuchun Zhao, Robert Tibshirani, June H Myklebust, Mrinmoy Sanyal, Rosemary Fernandez, Dita Gratzinger, Robert J Marinelli, Zhi Shun Lu, Anna Wong,…

  Source: Human pathology. 2010 Feb

  View Full Text

• Inhibitory effects and target genes of bone morphogenetic protein 6 in Jurkat TAg cells.

  Bone morphogenetic proteins (BMP) are multifunctional cytokines that belong to the TGF-beta superfamily. BMP have been shown to regulate haematopoieti…

  Authors: Einar A Sivertsen, Kanutte Huse, Marit E Hystad, Christian Kersten, Erlend B Smeland, June H Myklebust

  Source: European journal of immunology. 2007 Oct

  View Full Text

• BMP-6 inhibits human bone marrow B lymphopoiesis--upregulation of Id1 and Id3.

  OBJECTIVE: In mammals, factors produced by bone marrow (BM) stromal cells are instrumental in orchestrating the developmental process of B lymphocytes…

  Authors: Christian Kersten, Guri Dosen, June H Myklebust, Einar A Sivertsen, Marit E Hystad, Erlend B Smeland, Edith Rian

  Source: Experimental hematology. 2006 Jan

  View Full Text

• Characterization of early stages of human B cell development by gene expression profiling.

  We have characterized several stages of normal human B cell development in adult bone marrow by gene expression profiling of hemopoietic stem cells, e…

  Authors: Marit E Hystad, June H Myklebust, Trond H Bø, Einar A Sivertsen, Edith Rian, Lise Forfang, Else Munthe, Andreas Rosenwald, Michael Chiorazzi, Inge Jonassen,…

  Source: Journal of immunology (Baltimore, Md. : 1950). 2007 Sep 15

  View Full Text

• BMP-6 inhibits growth of mature human B cells; induction of Smad phosphorylation and upregulation of Id1.

  BACKGROUND: Bone morphogenetic proteins (BMPs) belong to the TGF-beta superfamily and are secreted proteins with pleiotropic roles in many different c…

  Authors: Christian Kersten, Einar A Sivertsen, Marit E Hystad, Lise Forfang, Erlend B Smeland, June H Myklebust

  Source: BMC immunology. 2005

  View Full Text

• PU.1 protein expression has a positive linear association with protein expression of germinal centre B cell genes including BCL-6, CD10, CD20 and CD22: identification of PU.1 putative binding sites in the BCL-6 promotor.

  The transcription factor PU.1 has been shown to be crucial for the early stages of B cell development but its function at later stages of B cell devel…

  Authors: Emina Torlakovic, Agnieszka Malecka, June H Myklebust, Anne Tierens, Hans-Christian Aasheim, Jahn M Nesland, Erlend Smeland, Stein Kvaløy, Jan Delabie

  Source: The Journal of pathology. 2005 Jul

  View Full Text