1 to 5 of 5 literature results

• Role of the hypothalamic-pituitary-thyroid axis in metabolic regulation by JNK1.

  The cJun N-terminal kinase 1 (JNK1) is implicated in diet-induced obesity. Indeed, germline ablation of the murine Jnk1 gene prevents diet-induced obe…

  Authors: Guadalupe Sabio, Julie Cavanagh-Kyros, Tamera Barrett, Dae Young Jung, Hwi Jin Ko, Helena Ong, Caroline Morel, Alfonso Mora, Judith Reilly, Jason K Kim,…

  Source: Genes & development. 2010 Feb 1

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• Functional cooperation of the proapoptotic Bcl2 family proteins Bmf and Bim in vivo.

  Bcl2-modifying factor (Bmf) is a member of the BH3-only group of proapoptotic proteins. To test the role of Bmf in vivo, we constructed mice with a se…

  Authors: Anette Hübner, Julie Cavanagh-Kyros, Mercedes Rincon, Richard A Flavell, Roger J Davis

  Source: Molecular and cellular biology. 2010 Jan

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• Requirement of JIP scaffold proteins for NMDA-mediated signal transduction.

  JIP scaffold proteins are implicated in the regulation of protein kinase signal transduction pathways. To test the physiological role of these scaffol…

  Authors: Norman J Kennedy, Gilles Martin, Anka G Ehrhardt, Julie Cavanagh-Kyros, Chia-Yi Kuan, Pasko Rakic, Richard A Flavell, Steven N Treistman, Roger J Davis

  Source: Genes & development. 2007 Sep 15

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• Role of muscle c-Jun NH2-terminal kinase 1 in obesity-induced insulin resistance.

  Obesity caused by feeding of a high-fat diet (HFD) is associated with an increased activation of c-Jun NH(2)-terminal kinase 1 (JNK1). Activated JNK1 …

  Authors: Guadalupe Sabio, Norman J Kennedy, Julie Cavanagh-Kyros, Dae Young Jung, Hwi Jin Ko, Helena Ong, Tamera Barrett, Jason K Kim, Roger J Davis

  Source: Molecular and cellular biology. 2010 Jan

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• Prevention of steatosis by hepatic JNK1.

  Nonalcoholic steatosis (fatty liver) is a major cause of liver dysfunction that is associated with insulin resistance and metabolic syndrome. The cJun…

  Authors: Guadalupe Sabio, Julie Cavanagh-Kyros, Hwi Jin Ko, Dae Young Jung, Susan Gray, John Y Jun, Tamera Barrett, Alfonso Mora, Jason K Kim, Roger J Davis

  Source: Cell metabolism. 2009 Dec

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