1 to 10 of 30 literature results

• Common variants in TMPRSS6 are associated with iron status and erythrocyte volume.

  We report a genome-wide association study to iron status. We identify an association of SNPs in TPMRSS6 to serum iron (rs855791, combined P = 1.5 x 10…

  Authors: Beben Benyamin, Manuel A R Ferreira, Gonneke Willemsen, Scott Gordon, Rita P S Middelberg, Brian P McEvoy, Jouke-Jan Hottenga, Anjali K Henders, Megan J Campbell, Leanne Wallace,…

  Source: Nature genetics. 2009 Nov

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• Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.

  Recent genome-wide association (GWA) studies of lipids have been conducted in samples ascertained for other phenotypes, particularly diabetes. Here we…

  Authors: Yurii S Aulchenko, Samuli Ripatti, Ida Lindqvist, Dorret Boomsma, Iris M Heid, Peter P Pramstaller, Brenda W J H Penninx, A Cecile J W Janssens, James F Wilson, Tim Spector,…

  Source: Nature genetics. 2009 Jan

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• HLA and genomewide allele sharing in dizygotic twins.

  Gametic selection during fertilization or the effects of specific genotypes on the viability of embryos may cause a skewed transmission of chromosomes…

  Authors: Grant W Montgomery, Gu Zhu, Jouke Jan Hottenga, David L Duffy, Andrew C Heath, Dorret I Boomsma, Nicholas G Martin, Peter M Visscher

  Source: American journal of human genetics. 2006 Dec

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• Genome partitioning of genetic variation for height from 11,214 sibling pairs.

  Height has been used for more than a century as a model by which to understand quantitative genetic variation in humans. We report that the entire gen…

  Authors: Peter M Visscher, Stuart Macgregor, Beben Benyamin, Gu Zhu, Scott Gordon, Sarah Medland, William G Hill, Jouke-Jan Hottenga, Gonneke Willemsen, Dorret I Boomsma,…

  Source: American journal of human genetics. 2007 Nov

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• Genome-wide association study of smoking initiation and current smoking.

  For the identification of genes associated with smoking initiation and current smoking, genome-wide association analyses were carried out in 3497 subj…

  Authors: Jacqueline M Vink, August B Smit, Eco J C de Geus, Patrick Sullivan, Gonneke Willemsen, Jouke-Jan Hottenga, Johannes H Smit, Witte J Hoogendijk, Frans G Zitman, Leena Peltonen,…

  Source: American journal of human genetics. 2009 Mar

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• Sequence variants in three loci influence monocyte counts and erythrocyte volume.

  Blood cells participate in vital physiological processes, and their numbers are tightly regulated so that homeostasis is maintained. Disruption of key…

  Authors: Manuel A R Ferreira, Jouke-Jan Hottenga, Nicole M Warrington, Sarah E Medland, Gonneke Willemsen, Robert W Lawrence, Scott Gordon, Eco J C de Geus, Anjali K Henders, Johannes H Smit,…

  Source: American journal of human genetics. 2009 Nov

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• Variants in MTNR1B influence fasting glucose levels.

  To identify previously unknown genetic loci associated with fasting glucose concentrations, we examined the leading association signals in ten genome-…

  Authors: Inga Prokopenko, Claudia Langenberg, Jose C Florez, Richa Saxena, Nicole Soranzo, Gudmar Thorleifsson, Ruth J F Loos, Alisa K Manning, Anne U Jackson, Yurii Aulchenko,…

  Source: Nature genetics. 2009 Jan

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• New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk.

  Levels of circulating glucose are tightly regulated. To identify new loci influencing glycemic traits, we performed meta-analyses of 21 genome-wide as…

  Authors: Josée Dupuis, Claudia Langenberg, Inga Prokopenko, Richa Saxena, Nicole Soranzo, Anne U Jackson, Eleanor Wheeler, Nicole L Glazer, Nabila Bouatia-Naji, Anna L Gloyn,…

  Source: Nature genetics. 2010 Feb

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• Genome-wide scan for blood pressure in Australian and Dutch subjects suggests linkage at 5P, 14Q, and 17P.

  Large-scale studies estimate the heritability of blood pressure at approximately 50%. We carried out a genome-wide linkage analysis to search for chro…

  Authors: Jouke-Jan Hottenga, John B Whitfield, Danielle Posthuma, Gonneke Willemsen, Eco J C de Geus, Nicholas G Martin, Dorret I Boomsma

  Source: Hypertension. 2007 Apr

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• A genome-wide association study of northwestern Europeans involves the C-type natriuretic peptide signaling pathway in the etiology of human height variation.

  Northwestern Europeans are among the tallest of human populations. The increase in body height in these people appears to have reached a plateau, sugg…

  Authors: Karol Estrada, Michael Krawczak, Stefan Schreiber, Kate van Duijn, Lisette Stolk, Joyce B J van Meurs, Fan Liu, Brenda W J H Penninx, Jan H Smit, Nicole Vogelzangs,…

  Source: Human molecular genetics. 2009 Sep 15

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