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• PPAR-delta senses and orchestrates clearance of apoptotic cells to promote tolerance.

  Macrophages rapidly engulf apoptotic cells to limit the release of noxious cellular contents and to restrict autoimmune responses against self antigen…

  Authors: Lata Mukundan, Justin I Odegaard, Christine R Morel, Jose E Heredia, Julia W Mwangi, Roberto R Ricardo-Gonzalez, Y P Sharon Goh, Alex Red Eagle, Shannon E Dunn, Jennifer U H Awakuni,…

  Source: Nature medicine. 2009 Nov

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• TRB3 links the E3 ubiquitin ligase COP1 to lipid metabolism.

  During fasting, increased concentrations of circulating catecholamines promote the mobilization of lipid stores from adipose tissue in part by phospho…

  Authors: Ling Qi, Jose E Heredia, Judith Y Altarejos, Robert Screaton, Naomi Goebel, Sherry Niessen, Ian X Macleod, Chong Wee Liew, Rohit N Kulkarni, James Bain,…

  Source: Science (New York, N.Y.). 2006 Jun 23

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