1 to 10 of 12 literature results

• Foxp3+ regulatory T cells: differentiation, specification, subphenotypes.

  Regulatory T cells (T(reg) cells) characterized by expression of the transcription factor Foxp3 play a key role in immune homeostasis. Rather than a m…

  Authors: Markus Feuerer, Jonathan A Hill, Diane Mathis, Christophe Benoist

  Source: Nature immunology. 2009 Jul

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• Treg cells: guardians for life.

  Regulatory T cells expressing the transcription factor Foxp3 are known to control autoreactivity during and subsequent to the development of the perip…

  Authors: Jonathan A Hill, Christophe Benoist, Diane Mathis

  Source: Nature immunology. 2007 Feb

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• Retinoic acid enhances Foxp3 induction indirectly by relieving inhibition from CD4+CD44hi Cells.

  CD4(+)Foxp3(+) regulatory T (Treg) cells originate primarily from thymic differentiation, but conversion of mature T lymphocytes to Foxp3 positivity c…

  Authors: Jonathan A Hill, Jason A Hall, Cheng-Ming Sun, Qi Cai, Norbert Ghyselinck, Pierre Chambon, Yasmine Belkaid, Diane Mathis, Christophe Benoist

  Source: Immunity. 2008 Nov 14

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• Foxp3 transcription-factor-dependent and -independent regulation of the regulatory T cell transcriptional signature.

  The CD4(+)CD25(+) lineage of regulatory T (Treg) cells plays a key role in controlling immune and autoimmune responses and is characterized by a uniqu…

  Authors: Jonathan A Hill, Markus Feuerer, Kaley Tash, Sokol Haxhinasto, Jasmine Perez, Rachel Melamed, Diane Mathis, Christophe Benoist

  Source: Immunity. 2007 Nov

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• An intriguing relationship between the immune response to citrullinated vimentin and the HLA shared epitope: comment on the article by Verpoort et al.

  Authors: David A Bell, Jonathan A Hill, Ewa Cairns

  Source: Arthritis and rheumatism. 2008 Oct

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• The relationship between predicted peptide-MHC class II affinity and T-cell activation in a HLA-DRbeta1*0401 transgenic mouse model.

  The HLA-DRB1*0401 MHC class II molecule (DR4) is genetically associated with rheumatoid arthritis. It has been proposed that this MHC class II molecul…

  Authors: Jonathan A Hill, Dequn Wang, Anthony M Jevnikar, Ewa Cairns, David A Bell

  Source: Arthritis research & therapy. 2003

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• The influence of HLA-DR4 (0401) on the immune response to type II collagen and the development of collagen induced arthritis in mice.

  Rheumatoid arthritis (RA) is an autoimmune disease that is genetically associated with the MHC class II molecule HLA-DRbeta1*0401 (DR4). In order to d…

  Authors: Dequn Wang, Jonathan A Hill, Ewa Cairns, David A Bell

  Source: Journal of autoimmunity. 2002 Mar

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• Induction of transient arthritis by the adoptive transfer of a collagen II specific Th1 clone to HLA-DR4 (B1*0401) transgenic mice.

  Collagen II arthritis (CIA) represents an animal model of human RA that can be induced in DBA/1J (H-2(q)) but not in C57BL/6 mice (H-2(b)). A vigorous…

  Authors: Dequn Wang, Jonathan A Hill, Anthony M Jevnikar, Ewa Cairns, David A Bell

  Source: Journal of autoimmunity. 2002 Aug-Sep

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• Arthritis induced by posttranslationally modified (citrullinated) fibrinogen in DR4-IE transgenic mice.

  Rheumatoid arthritis (RA) is a common autoimmune disease that afflicts the synovium of diarthrodial joints. The pathogenic mechanisms inciting this di…

  Authors: Jonathan A Hill, David A Bell, William Brintnell, David Yue, Bret Wehrli, Anthony M Jevnikar, David M Lee, Wolfgang Hueber, William H Robinson, Ewa Cairns

  Source: The Journal of experimental medicine. 2008 Apr 14

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• Serum autoantibodies that bind citrullinated fibrinogen are frequently found in patients with rheumatoid arthritis.

  OBJECTIVE: Autoantibodies that bind citrullinated antigens are a sensitive and specific marker for rheumatoid arthritis (RA). While synthetic cyclic c…

  Authors: Jonathan A Hill, Jamal Al-Bishri, Dafna D Gladman, Ewa Cairns, David A Bell

  Source: The Journal of rheumatology. 2006 Nov

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