1 to 6 of 6 literature results

• The genetics of Crohn's disease.

  From epidemiological data, based on concordance data in family studies, via linkage analysis to genome-wide association studies, we and others have ac…

  Authors: Johan Van Limbergen, David C Wilson, Jack Satsangi

  Source: Annual review of genomics and human genetics. 2009

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• Definition of phenotypic characteristics of childhood-onset inflammatory bowel disease.

  BACKGROUND & AIMS: Childhood-onset inflammatory bowel disease (IBD) might be etiologically different from adult-onset IBD. We analyzed disease phenoty…

  Authors: Johan Van Limbergen, Richard K Russell, Hazel E Drummond, Marian C Aldhous, Nicola K Round, Elaine R Nimmo, Linda Smith, Peter M Gillett, Paraic McGrogan, Lawrence T Weaver,…

  Source: Gastroenterology. 2008 Oct

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• Diverse genome-wide association studies associate the IL12/IL23 pathway with Crohn Disease.

  Previous genome-wide association (GWA) studies typically focus on single-locus analysis, which may not have the power to detect the majority of genuin…

  Authors: Kai Wang, Haitao Zhang, Subra Kugathasan, Vito Annese, Jonathan P Bradfield, Richard K Russell, Patrick M A Sleiman, Marcin Imielinski, Joseph Glessner, Cuiping Hou,…

  Source: American journal of human genetics. 2009 Mar

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• Investigation of NOD1/CARD4 variation in inflammatory bowel disease using a haplotype-tagging strategy.

  Both NOD1/CARD4 and NOD2/CARD15 are intracellular pattern-recognition receptors involved in the innate immune response. Germline NOD2/CARD15 variation…

  Authors: Johan Van Limbergen, Elaine R Nimmo, Richard K Russell, Hazel E Drummond, Linda Smith, Niall H Anderson, Gail Davies, Ian D Arnott, David C Wilson, Jack Satsangi

  Source: Human molecular genetics. 2007 Sep 15

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• Genetics of the innate immune response in inflammatory bowel disease.

  The discovery of nucleotide-binding oligomerization domain 2/caspase recruitment domain-containing protein 15 (NOD2/CARD15) as the first susceptibilit…

  Authors: Johan Van Limbergen, Richard K Russell, Elaine R Nimmo, Gwo-Tzer Ho, Ian D Arnott, David C Wilson, Jack Satsangi

  Source: Inflammatory bowel diseases. 2007 Mar

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• The genetics of inflammatory bowel disease.

  Great progress in the understanding of the molecular genetics of inflammatory bowel disease (IBD) has been made over the last 10 years. Strong epidemi…

  Authors: Johan Van Limbergen, Richard K Russell, Elaine R Nimmo, Jack Satsangi

  Source: The American journal of gastroenterology. 2007 Dec

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