1 to 10 of 79 literature results

• TP53 mutation analysis of malignant peripheral nerve sheath tumors.

  Mutations in TP53 underlie the development of malignant peripheral nerve sheath tumors (MPNSTs) in animal models, but there is controversy regarding t…

  Authors: Robert M Verdijk, Michael A den Bakker, Hendrikus J Dubbink, Wim C J Hop, Winand N M Dinjens, Johan M Kros

  Source: Journal of neuropathology and experimental neurology. 2010 Jan

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• Predictive and prognostic markers in neuro-oncology.

  Over the past few years molecular assays have been introduced to aid in typing and grading of gliomas. This is the result of improved understanding of…

  Authors: Martin J van den Bent, Johan M Kros

  Source: Journal of neuropathology and experimental neurology. 2007 Dec

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• Increased levels of circulating endothelial progenitor cells and circulating endothelial nitric oxide synthase in patients with gliomas.

  OBJECTIVE: Gliomas are among the highest vascularized tumors. We hypothesized that patients with gliomas have increased levels of circulating endothel…

  Authors: Ping-Pin Zheng, Wim C Hop, Theodorus M Luider, Peter A E Sillevis Smitt, Johan M Kros

  Source: Annals of neurology. 2007 Jul

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• Mutation in the AP4M1 gene provides a model for neuroaxonal injury in cerebral palsy.

  Cerebral palsy due to perinatal injury to cerebral white matter is usually not caused by genetic mutations, but by ischemia and/or inflammation. Here,…

  Authors: Annemieke J M H Verkerk, Rachel Schot, Belinda Dumee, Karlijn Schellekens, Sigrid Swagemakers, Aida M Bertoli-Avella, Maarten H Lequin, Jeroen Dudink, Paul Govaert, A L van Zwol,…

  Source: American journal of human genetics. 2009 Jul

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• A crucial role of caldesmon in vascular development in vivo.

  AIMS: We explored the in vivo effects of knockdown of caldesmon on vascular development in zebrafish. METHODS AND RESULTS: We investigated the effects…

  Authors: Ping-Pin Zheng, Lies-Anne Severijnen, Marcel van der Weiden, Rob Willemsen, Johan M Kros

  Source: Cardiovascular research. 2009 Feb 1

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• Intrinsic gene expression profiles of gliomas are a better predictor of survival than histology.

  Gliomas are the most common primary brain tumors with heterogeneous morphology and variable prognosis. Treatment decisions in patients rely mainly on …

  Authors: Lonneke A M Gravendeel, Mathilde C M Kouwenhoven, Olivier Gevaert, Johan J de Rooi, Andrew P Stubbs, J Elza Duijm, Anneleen Daemen, Fonnet E Bleeker, Linda B C Bralten, Nanne K Kloosterhof,…

  Source: Cancer research. 2009 Dec 1

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• Sample preparation issues for tissue imaging by imaging MS.

  Imaging MS is a powerful technique that combines the chemical and spatial analysis of surfaces. It allows spatial localization of multiple different c…

  Authors: Başak Kükrer Kaletaş, Ingrid M van der Wiel, Jonathan Stauber, Lennard J. Dekker, Coşkun Güzel, Johan M Kros, Theo M Luider, Ron M A Heeren

  Source: Proteomics. 2009 May

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• Segregation of non-p.R132H mutations in IDH1 in distinct molecular subtypes of glioma.

  Mutations in the gene encoding the isocitrate dehydrogenase 1 gene (IDH1) occur at a high frequency (up to 80%) in many different subtypes of glioma. …

  Authors: Lonneke A M Gravendeel, Nanne K Kloosterhof, Linda B C Bralten, Ronald van Marion, Hendrikus Jan Dubbink, Winand Dinjens, Fonnet E Bleeker, Casper C Hoogenraad, Erna Michiels, Johan M Kros,…

  Source: Human mutation. 2010 Mar

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• Haemoglobin staining for in vivo portraying of functional vasculature in experimental zebrafish embryos.

  Characterization of functional vessels is required either for monitoring hemodynamics or patterning of functional vasculature in experimental models. …

  Authors: Ping-Pin Zheng, Lies-Anne Severijnen, Rob Willemsen, Johan M Kros

  Source: Biochemical and biophysical research communications. 2009 Mar 20

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• Identification of differentially regulated splice variants and novel exons in glial brain tumors using exon expression arrays.

  Aberrant splice variants are involved in the initiation and/or progression of glial brain tumors. We therefore set out to identify splice variants tha…

  Authors: Pim J French, Justine Peeters, Sebastiaan Horsman, Elza Duijm, Ivar Siccama, Martin J van den Bent, Theo M Luider, Johan M Kros, Peter van der Spek, Peter A Sillevis Smitt

  Source: Cancer research. 2007 Jun 15

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