1 to 7 of 7 literature results

• Asymmetric segregation of the tumor suppressor brat regulates self-renewal in Drosophila neural stem cells.

  How stem cells generate both differentiating and self-renewing daughter cells is unclear. Here, we show that Drosophila larval neuroblasts-stem cell-l…

  Authors: Joerg Betschinger, Karl Mechtler, Juergen A Knoblich

  Source: Cell. 2006 Mar 24

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• Mei-P26 regulates microRNAs and cell growth in the Drosophila ovarian stem cell lineage.

  Drosophila neuroblasts and ovarian stem cells are well characterized models for stem cell biology. In both cell types, one daughter cell self-renews c…

  Authors: Ralph A Neumüller, Joerg Betschinger, Anja Fischer, Natascha Bushati, Ingrid Poernbacher, Karl Mechtler, Stephen M Cohen, Juergen A Knoblich

  Source: Nature. 2008 Jul 10

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• The tumor suppressors Brat and Numb regulate transit-amplifying neuroblast lineages in Drosophila.

  In both vertebrates and insects, neurons typically arise from neural stem cells or terminally dividing intermediate progenitors. Here, we describe ano…

  Authors: Sarah K Bowman, Vivien Rolland, Joerg Betschinger, Kaolin A Kinsey, Gregory Emery, Juergen A Knoblich

  Source: Developmental cell. 2008 Apr

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• Sequential roles of Cdc42, Par-6, aPKC, and Lgl in the establishment of epithelial polarity during Drosophila embryogenesis.

  How epithelial cells subdivide their plasma membrane into an apical and a basolateral domain is largely unclear. In Drosophila embryos, epithelial cel…

  Authors: Andrea Hutterer, Joerg Betschinger, Mark Petronczki, Juergen A Knoblich

  Source: Developmental cell. 2004 Jun

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• Fragile X protein functions with lgl and the par complex in flies and mice.

  Fragile X syndrome, the most common form of inherited mental retardation, is caused by loss of function for the Fragile X Mental Retardation 1 gene (F…

  Authors: Daniela C Zarnescu, Peng Jin, Joerg Betschinger, Mika Nakamoto, Yan Wang, Thomas C Dockendorff, Yue Feng, Thomas A Jongens, John C Sisson, Juergen A Knoblich,…

  Source: Developmental cell. 2005 Jan

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• Phosphorylation-induced autoinhibition regulates the cytoskeletal protein Lethal (2) giant larvae.

  During asymmetric cell division, cell fate determinants localize asymmetrically and segregate into one of the two daughter cells. In Drosophila neurob…

  Authors: Joerg Betschinger, Frank Eisenhaber, Juergen A Knoblich

  Source: Current biology : CB. 2005 Feb 8

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• Shortstop recruits EB1/APC1 and promotes microtubule assembly at the muscle-tendon junction.

  BACKGROUND: Shot (previously named Kakapo), is a Drosophila Plakin family member containing both Actin binding and microtubule binding domains. In Dro…

  Authors: Arul Subramanian, Andreas Prokop, Misato Yamamoto, Kaoru Sugimura, Tadashi Uemura, Joerg Betschinger, Juergen A Knoblich, Talila Volk

  Source: Current biology : CB. 2003 Jul 1

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