1 to 10 of 13 literature results

• Mechanism of folding chamber closure in a group II chaperonin.

  Group II chaperonins are essential mediators of cellular protein folding in eukaryotes and archaea. These oligomeric protein machines, approximately 1…

  Authors: Junjie Zhang, Matthew L Baker, Gunnar F Schröder, Nicholai R Douglas, Stefanie Reissmann, Joanita Jakana, Matthew Dougherty, Caroline J Fu, Michael Levitt, Steven J Ludtke,…

  Source: Nature. 2010 Jan 21

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• Backbone structure of the infectious epsilon15 virus capsid revealed by electron cryomicroscopy.

  A half-century after the determination of the first three-dimensional crystal structure of a protein, more than 40,000 structures ranging from single …

  Authors: Wen Jiang, Matthew L Baker, Joanita Jakana, Peter R Weigele, Jonathan King, Wah Chiu

  Source: Nature. 2008 Feb 28

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• Structure of epsilon15 bacteriophage reveals genome organization and DNA packaging/injection apparatus.

  The critical viral components for packaging DNA, recognizing and binding to host cells, and injecting the condensed DNA into the host are organized at…

  Authors: Wen Jiang, Juan Chang, Joanita Jakana, Peter Weigele, Jonathan King, Wah Chiu

  Source: Nature. 2006 Feb 2

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• Radiation damage effects at four specimen temperatures from 4 to 100 K.

  Radiation damage is the primary factor that limits resolution in electron cryo-microscopy (cryo-EM) of frozen-hydrated biological samples. Negative ef…

  Authors: Benjamin E Bammes, Joanita Jakana, Michael F Schmid, Wah Chiu

  Source: Journal of structural biology. 2010 Mar

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• Achievable resolution from images of biological specimens acquired from a 4k x 4k CCD camera in a 300-kV electron cryomicroscope.

  Bacteriorhodopsin and epsilon 15 bacteriophage were used as biological test specimens to evaluate the potential structural resolution with images capt…

  Authors: Dong-Hua Chen, Joanita Jakana, Xiangan Liu, Michael F Schmid, Wah Chiu

  Source: Journal of structural biology. 2008 Jul

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• Averaging tens to hundreds of icosahedral particle images to resolve protein secondary structure elements using a Multi-Path Simulated Annealing optimization algorithm.

  Accurately determining a cryoEM particle's alignment parameters is crucial to high resolution single particle 3-D reconstruction. We developed Multi-P…

  Authors: Xiangan Liu, Wen Jiang, Joanita Jakana, Wah Chiu

  Source: Journal of structural biology. 2007 Oct

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• Assessing the capabilities of a 4kx4k CCD camera for electron cryo-microscopy at 300kV.

  CCD cameras have numerous advantages over photographic film for detecting electrons; however the point spread function of these cameras has not been s…

  Authors: Christopher R Booth, Joanita Jakana, Wah Chiu

  Source: Journal of structural biology. 2006 Dec

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• JADAS: a customizable automated data acquisition system and its application to ice-embedded single particles.

  The JEOL Automated Data Acquisition System (JADAS) is a software system built for the latest generation of the JEOL Transmission Electron Microscopes.…

  Authors: Junjie Zhang, Natsuko Nakamura, Yuko Shimizu, Nathan Liang, Xiangan Liu, Joanita Jakana, Michael P Marsh, Christopher R Booth, Takao Shinkawa, Munetaka Nakata,…

  Source: Journal of structural biology. 2009 Jan

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• Electron cryo-microscopy of VAT, the archaeal p97/CDC48 homologue from Thermoplasma acidophilum.

  VAT (valosine containing protein-like ATPase from Thermoplasma acidophilum), an archaeal member of the AAA-family (ATPases associated with a variety o…

  Authors: Beate Rockel, Joanita Jakana, Wah Chiu, Wolfgang Baumeister

  Source: Journal of molecular biology. 2002 Apr 12

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• 4.0-A resolution cryo-EM structure of the mammalian chaperonin TRiC/CCT reveals its unique subunit arrangement.

  The essential double-ring eukaryotic chaperonin TRiC/CCT (TCP1-ring complex or chaperonin containing TCP1) assists the folding of approximately 5-10% …

  Authors: Yao Cong, Matthew L Baker, Joanita Jakana, David Woolford, Erik J Miller, Stefanie Reissmann, Ramya N Kumar, Alyssa M Redding-Johanson, Tanveer S Batth, Aindrila Mukhopadhyay,…

  Source: Proceedings of the National Academy of Sciences of the United States of America. 2010 Mar 16

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