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Steroid receptor coactivator-3 (SRC-3) is a transcriptional coactivator for nuclear receptors and other transcription factors. Although multiple physi…
Authors: Chundong Yu, Brian York, Shu Wang, Qin Feng, Jianming Xu, Bert W O'Malley
Source: Molecular cell. 2007 Mar 9
View Free Full TextIn breast cancer, steroid receptor coactivator-1 (SRC-1) expression positively correlates with HER2 expression and poor prognosis. In mouse mammary tu…
Authors: Li Qin, Zhaoliang Liu, Hongwu Chen, Jianming Xu
Source: Cancer research. 2009 May 1
View Full TextAlthough the LXXLL motif of nuclear receptor (NR) coactivators is essential for interaction with NRs, its role has not been assessed in unbiased anima…
Authors: Qingtian Li, Mei-Jin Chu, Jianming Xu
Source: Molecular and cellular biology. 2007 Dec
View Free Full TextSteroid receptor coactivator 3 (SRC-3/AIB1/ACTR/NCoA-3) is a transcriptional coactivator for nuclear receptors including vitamin D receptor (VDR). Gro…
Authors: Lan Liao, Xian Chen, Shu Wang, Albert F Parlow, Jianming Xu
Source: Molecular and cellular biology. 2008 Apr
View Free Full TextOverexpression of the oncogene amplified in breast cancer 1 (AIB1)/steroid receptor coactivator-3 (SRC-3) induces mammary tumorigenesis in mice. In br…
Authors: Mark P Fereshteh, Maddalena T Tilli, Sung Eun Kim, Jianming Xu, Bert W O'Malley, Anton Wellstein, Priscilla A Furth, Anna T Riegel
Source: Cancer research. 2008 May 15
View Full TextThe genetic changes and mechanisms underlying the progression of estrogen-dependent breast cancers to estrogen-independent, antiestrogen-resistant, an…
Authors: Yuhui Yuan, Li Qin, Dan Liu, Ray-Chang Wu, Paola Mussi, Suoling Zhou, Zhou Songyang, Jianming Xu
Source: Cancer research. 2007 Sep 1
View Free Full TextAlthough the amplified-in-breast cancer 1 (AIB1; SRC-3, ACTR, or NCoA3) was defined as a coactivator for androgen receptor (AR) by in vitro studies, i…
Authors: Arthur C-K Chung, Suoling Zhou, Lan Liao, Jean Ching-Yi Tien, Norman M Greenberg, Jianming Xu
Source: Cancer research. 2007 Jun 15
View Full TextAmplified-in-breast cancer 1 (AIB1) is an overexpressed transcriptional coactivator in breast cancer. Although overproduced AIB1 is oncogenic, its rol…
Authors: Li Qin, Lan Liao, Aisling Redmond, Leonie Young, Yuhui Yuan, Hongwu Chen, Bert W O'Malley, Jianming Xu
Source: Molecular and cellular biology. 2008 Oct
View Free Full TextOverexpression and activation of the steroid receptor coactivator amplified in breast cancer 1 (AIB1)/steroid receptor coactivator-3 (SRC-3) have been…
Authors: Annabell S Oh, John T Lahusen, Christopher D Chien, Mark P Fereshteh, Xiaolong Zhang, Sivanesan Dakshanamurthy, Jianming Xu, Benjamin L Kagan, Anton Wellstein, Anna T Riegel
Source: Molecular and cellular biology. 2008 Nov
View Free Full TextThe tumor suppressor p53 is important for inhibiting the development of breast carcinomas. However, little is known about the effects of increased p53…
Authors: Catherine E Gatza, Melissa Dumble, Frances Kittrell, David G Edwards, Robert K Dearth, Adrian V Lee, Jianming Xu, Daniel Medina, Lawrence A Donehower
Source: Developmental biology. 2008 Jan 1
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