1 to 10 of 32 literature results

• Human marginal zone B cells.

  Human marginal zone (MZ) B cells are, in a sense, a new entity. Although they share many properties with their mouse counterpart, they also display st…

  Authors: Jean-Claude Weill, Sandra Weller, Claude-Agnès Reynaud

  Source: Annual review of immunology. 2009

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• Multiple layers of B cell memory with different effector functions.

  Memory B cells are at the center of longstanding controversies regarding the presence of antigen for their survival and their re-engagement in germina…

  Authors: Ismail Dogan, Barbara Bertocci, Valérie Vilmont, Frédéric Delbos, Jérome Mégret, Sébastien Storck, Claude-Agnès Reynaud, Jean-Claude Weill

  Source: Nature immunology. 2009 Dec

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• What role for AID: mutator, or assembler of the immunoglobulin mutasome?

  Activation-induced cytidine deaminase (AID) has been shown to trigger three mechanisms for diversifying immunoglobulin genes--somatic hypermutation, i…

  Authors: Claude-Agnès Reynaud, Said Aoufouchi, Ahmad Faili, Jean-Claude Weill

  Source: Nature immunology. 2003 Jul

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• Nonoverlapping functions of DNA polymerases mu, lambda, and terminal deoxynucleotidyltransferase during immunoglobulin V(D)J recombination in vivo.

  DNA polymerases mu (pol mu), lambda (pol lambda), and terminal deoxynucleotidyltransferase (TdT) are enzymes of the pol X family that share homology i…

  Authors: Barbara Bertocci, Annie De Smet, Jean-Claude Weill, Claude-Agnès Reynaud

  Source: Immunity. 2006 Jul

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• Induction of somatic hypermutation in immunoglobulin genes is dependent on DNA polymerase iota.

  Somatic hypermutation of immunoglobulin genes is a unique, targeted, adaptive process. While B cells are engaged in germinal centres in T-dependent re…

  Authors: Ahmad Faili, Said Aoufouchi, Eric Flatter, Quentin Guéranger, Claude-Agnès Reynaud, Jean-Claude Weill

  Source: Nature. 2002 Oct 31

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• RPA tightens AID to DNA...editing.

  Authors: Jean-Claude Weill, Claude-Agnès Reynaud

  Source: Nature immunology. 2004 Sep

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• Immunoglobulin kappa light chain gene rearrangement is impaired in mice deficient for DNA polymerase mu.

  DNA polymerase mu (pol mu) is a template-dependent polymerase closely related to the lymphoid-specific enzyme terminal deoxynucleotidyl transferase (T…

  Authors: Barbara Bertocci, Annie De Smet, Claudia Berek, Jean-Claude Weill, Claude-Agnès Reynaud

  Source: Immunity. 2003 Aug

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• AID-dependent somatic hypermutation occurs as a DNA single-strand event in the BL2 cell line.

  Immunoglobulin (Ig) gene hypermutation can be induced in the BL2 Burkitt's lymphoma cell line by IgM cross-linking and coculture with normal or transf…

  Authors: Ahmad Faili, Said Aoufouchi, Quentin Guéranger, Carole Zober, Anne Léon, Barbara Bertocci, Jean-Claude Weill, Claude-Agnès Reynaud

  Source: Nature immunology. 2002 Sep

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• The human spleen is a major reservoir for long-lived vaccinia virus-specific memory B cells.

  The fact that you can vaccinate a child at 5 years of age and find lymphoid B cells and antibodies specific for this vaccination 70 years later remain…

  Authors: Maria Mamani-Matsuda, Antonio Cosma, Sandra Weller, Ahmad Faili, Caroline Staib, Loïc Garçon, Olivier Hermine, Odile Beyne-Rauzy, Claire Fieschi, Jacques-Olivier Pers,…

  Source: Blood. 2008 May 1

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• Vaccination against encapsulated bacteria in humans: paradoxes.

  Authors: Sandra Weller, Claude-Agnès Reynaud, Jean-Claude Weill

  Source: Trends in immunology. 2005 Feb

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