Click on one of these terms to refine your search
1 to 10 of 25 literature results
BRCA1, a breast and ovarian cancer-suppressor gene, exerts tumor-suppressing functions that appear to be associated, at least in part, with its DNA re…
Authors: Daniel P Silver, Stoil D Dimitrov, Jean Feunteun, Rebecca Gelman, Ronny Drapkin, Shihua D Lu, Elena Shestakova, Soundarapandian Velmurugan, Nicholas Denunzio, Serban Dragomir,…
Source: Cell. 2007 Mar 9
View Full TextBreast tumors with a germ-line mutation of BRCA1 (BRCA1 tumors) and basal-like carcinoma (BLC) are associated with a high rate of TP53 mutation. Becau…
Authors: Elodie Manié, Anne Vincent-Salomon, Jacqueline Lehmann-Che, Gaelle Pierron, Elisabeth Turpin, Mathilde Warcoin, Nadège Gruel, Ingrid Lebigot, Xavier Sastre-Garau, Rosette Lidereau,…
Source: Cancer research. 2009 Jan 15
View Full TextBRCA1, a breast and ovarian tumor suppressor, colocalizes with markers of the inactive X chromosome (Xi) on Xi in female somatic cells and associates …
Authors: Shridar Ganesan, Daniel P Silver, Roger A Greenberg, Dror Avni, Ronny Drapkin, Alexander Miron, Samuel C Mok, Voahangy Randrianarison, Steven Brodie, Jennifer Salstrom,…
Source: Cell. 2002 Nov 1
View Full TextThe physiopathology of cancer cells is the result of very complex signaling networks that represent in many cases distortions of the orderly networks …
Authors: Enrico Mihich, Jean Feunteun, Stephen Friend
Source: Cancer research. 2002 Jul 1
View Full TextWe have recently demonstrated that heterochromatin HP1 proteins are aberrantly distributed in lymphocytes of patients with immunodeficiency, centromer…
Authors: Judith J Luciani, Danielle Depetris, Yves Usson, Catherine Metzler-Guillemain, Cecile Mignon-Ravix, Micheal J Mitchell, Andre Megarbane, Pierre Sarda, Huseyin Sirma, Anne Moncla,…
Source: Journal of cell science. 2006 Jun 15
View Full TextIt is believed that polyploidy induces an orchestrated increase in gene expression. To know whether all alleles remain functional during megakaryocyte…
Authors: Hana Raslova, Lydia Roy, Claire Vourc'h, Jean Pierre Le Couedic, Olivier Brison, Didier Metivier, Jean Feunteun, Guido Kroemer, Najet Debili, William Vainchenker
Source: Blood. 2003 Jan 15
View Full TextBCR-ABL fusion oncogene is the molecular hallmark of chronic myelogenous leukemia (CML), a condition characterized by a progression from a chronic to …
Authors: Eric Deutsch, Sylvie Jarrousse, Dorothee Buet, Aymeric Dugray, Marie-Laure Bonnet, Marie-Catherine Vozenin-Brotons, Francois Guilhot, Ali G Turhan, Jean Feunteun, Jean Bourhis
Source: Blood. 2003 Jun 1
View Full TextDownregulation of proapoptotic molecules like Fas or caspase 8, or upregulation of antiapoptotic molecules like FLICE inhibitory protein has been sugg…
Authors: Léa Tourneur, Sylvie Mistou, Francine-Marie Michiels, Valérie Devauchelle, Laurent Renia, Jean Feunteun, Gilles Chiocchia
Source: Oncogene. 2003 May 8
View Full TextA conflict in cell cycle progression or DNA damage can lead to mitotic catastrophe when the DNA structure checkpoints are inactivated, for instance wh…
Authors: Maria Castedo, Jean-Luc Perfettini, Thomas Roumier, Alexander Valent, Hana Raslova, Kenichi Yakushijin, David Horne, Jean Feunteun, Gilbert Lenoir, René Medema,…
Source: Oncogene. 2004 May 27
View Full TextThe absence of detectable germline TP53 mutations in a fraction of families with Li-Fraumeni syndrome (LFS) has suggested the involvement of other gen…
Authors: Gaëlle Bougeard, Laurence Brugières, Agnès Chompret, Paul Gesta, Françoise Charbonnier, Alexander Valent, Cosette Martin, Grégory Raux, Jean Feunteun, Brigitte Bressac-de Paillerets,…
Source: Oncogene. 2003 Feb 13
View Full Text