1 to 10 of 14 literature results

• Induction of immunological tolerance by apoptotic cells requires caspase-dependent oxidation of high-mobility group box-1 protein.

  The mammalian immune system discriminates between modes of cell death; necrosis often results in inflammation and adaptive immunity, whereas apoptosis…

  Authors: Hirotaka Kazama, Jean-Ehrland Ricci, John M Herndon, George Hoppe, Douglas R Green, Thomas A Ferguson

  Source: Immunity. 2008 Jul 18

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• GAPDH and autophagy preserve survival after apoptotic cytochrome c release in the absence of caspase activation.

  In cells undergoing apoptosis, mitochondrial outer-membrane permeabilization (MOMP) is followed by caspase activation promoted by released cytochrome …

  Authors: Anna Colell, Jean-Ehrland Ricci, Stephen Tait, Sandra Milasta, Ulrich Maurer, Lisa Bouchier-Hayes, Patrick Fitzgerald, Ana Guio-Carrion, Nigel J Waterhouse, Cindy Wei Li,…

  Source: Cell. 2007 Jun 1

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• Disruption of mitochondrial function during apoptosis is mediated by caspase cleavage of the p75 subunit of complex I of the electron transport chain.

  Mitochondrial outer membrane permeabilization and cytochrome c release promote caspase activation and execution of apoptosis through cleavage of speci…

  Authors: Jean-Ehrland Ricci, Cristina Muñoz-Pinedo, Patrick Fitzgerald, Béatrice Bailly-Maitre, Guy A Perkins, Nagendra Yadava, Immo E Scheffler, Mark H Ellisman, Douglas R Green

  Source: Cell. 2004 Jun 11

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• Modulation of caspase-independent cell death leads to resensitization of imatinib mesylate-resistant cells.

  Imatinib mesylate is widely used for the treatment of patients with chronic myelogenous leukemia (CML). This compound is very efficient in killing Bcr…

  Authors: Vanessa J Lavallard, Ludivine A Pradelli, Audrey Paul, Marie Bénéteau, Arnaud Jacquel, Patrick Auberger, Jean-Ehrland Ricci

  Source: Cancer research. 2009 Apr 1

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• A unified model for apical caspase activation.

  Apoptosis is orchestrated by the concerted action of caspases, activated in a minimal two-step proteolytic cascade. Existing data suggests that apical…

  Authors: Kelly M Boatright, Martin Renatus, Fiona L Scott, Sabina Sperandio, Hwain Shin, Irene M Pedersen, Jean Ehrland Ricci, Wade A Edris, Daniel P Sutherlin, Douglas R Green,…

  Source: Molecular cell. 2003 Feb

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• And all of a sudden it's over: mitochondrial outer-membrane permeabilization in apoptosis.

  Identification of pro-apoptotic activities for a variety of proteins normally resident in the mitochondrial inter-membrane space has substantiated the…

  Authors: Nigel J Waterhouse, Jean-Ehrland Ricci, Douglas R Green

  Source: Biochimie. 2002 Feb-Mar

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• Antagonism of chemokine receptor CXCR3 inhibits osteosarcoma metastasis to lungs.

  Metastasis continues to be the leading cause of mortality for patients with cancer. Several years ago, it became clear that chemokines and their recep…

  Authors: Emmanuelle Pradelli, Babou Karimdjee-Soilihi, Jean-François Michiels, Jean-Ehrland Ricci, Marie-Ange Millet, Fanny Vandenbos, Timothy J Sullivan, Tassie L Collins, Michael G Johnson, Julio C Medina,…

  Source: International journal of cancer. Journal international du cancer. 2009 Dec 1

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• Comparative proteomics study reveals that bacterial CpG motifs induce tumor cell autophagy in vitro and in vivo.

  Unmethylated CpG dinucleotides, present in bacterial DNA, are recognized in vertebrates via the Toll-like receptor 9 (TLR9) and are known to act as an…

  Authors: Samuel Bertin, Michel Samson, Catherine Pons, Jean-Marie Guigonis, Adolfo Gavelli, Patrick Baqué, Nicole Brossette, Sophie Pagnotta, Jean-Ehrland Ricci, Valérie Pierrefite-Carle

  Source: Molecular & cellular proteomics : MCP. 2008 Dec

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• The caspase-cleaved form of LYN mediates a psoriasis-like inflammatory syndrome in mice.

  We showed previously that Lyn is a substrate for caspases, a family of cysteine proteases, involved in the regulation of apoptosis and inflammation. H…

  Authors: Sandrine Marchetti, Parvati Gamas, Nathalie Belhacène, Sebastien Grosso, Ludivine A Pradelli, Pascal Colosetti, Claus Johansen, Lars Iversen, Marcel Deckert, Fréderic Luciano,…

  Source: The EMBO journal. 2009 Aug 19

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• Cytoprotective peptide humanin binds and inhibits proapoptotic Bcl-2/Bax family protein BimEL.

  Humanin (HN) is a recently identified endogenous peptide that protects cells against cytotoxicity induced by various stimuli. Recently, we showed that…

  Authors: Frederic Luciano, Dayong Zhai, Xiuwen Zhu, Beatrice Bailly-Maitre, Jean-Ehrland Ricci, Arnold C Satterthwait, John C Reed

  Source: The Journal of biological chemistry. 2005 Apr 22

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