1 to 10 of 19 literature results

• TMPRSS2-ERG gene fusion is not associated with outcome in patients treated by prostatectomy.

  A significant number of prostate cancers have been shown to have recurrent chromosomal rearrangements resulting in the fusion of the androgen-regulate…

  Authors: Anuradha Gopalan, Margaret A Leversha, Jaya M Satagopan, Qin Zhou, Hikmat A Al-Ahmadie, Samson W Fine, James A Eastham, Peter T Scardino, Howard I Scher, Satish K Tickoo,…

  Source: Cancer research. 2009 Feb 15

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• Study of Nevi in Children (SONIC): baseline findings and predictors of nevus count.

  The authors report baseline findings and predictors of nevus count (log total nevi) at the completion of year 1 (2004) of the first known population-b…

  Authors: Susan A Oliveria, Jaya M Satagopan, Alan C Geller, Stephen W Dusza, Martin A Weinstock, Marianne Berwick, Marilyn Bishop, Maureen K Heneghan, Allan C Halpern

  Source: American journal of epidemiology. 2009 Jan 1

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• Frequency of BRCA1 and BRCA2 mutations in unselected Ashkenazi Jewish patients with colorectal cancer.

  Mutations in BRCA1 and BRCA2 that predispose to breast and ovarian cancer are detected in approximately 2.5% of the Ashkenazi Jewish population. To ex…

  Authors: Tomas Kirchhoff, Jaya M Satagopan, Noah D Kauff, Helen Huang, Prema Kolachana, Crystal Palmer, Hannah Rapaport, Khedoudja Nafa, Nathan A Ellis, Kenneth Offit

  Source: Journal of the National Cancer Institute. 2004 Jan 7

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• Genetic heterogeneity among Fanconi anemia heterozygotes and risk of cancer.

  Fanconi anemia (FA) is a rare autosomal recessive disease characterized by a greatly increased risk of cancer among those diagnosed with the syndrome.…

  Authors: Marianne Berwick, Jaya M Satagopan, Leah Ben-Porat, Ann Carlson, Katherine Mah, Rashida Henry, Raffaella Diotti, Kelly Milton, Kanan Pujara, Tom Landers,…

  Source: Cancer research. 2007 Oct 1

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• Quantitative trait locus study design from an information perspective.

  We examine the efficiency of different genotyping and phenotyping strategies in inbred line crosses from an information perspective. This provides a m…

  Authors: Saunak Sen, Jaya M Satagopan, Gary A Churchill

  Source: Genetics. 2005 May

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• Age-adjusted International Prognostic Index predicts autologous stem cell transplantation outcome for patients with relapsed or primary refractory diffuse large B-cell lymphoma.

  Second-line chemotherapy followed by high-dose therapy (HDT) with autologous stem cell transplantation (ASCT) cures less than half of the patients wit…

  Authors: Paul A Hamlin, Andrew D Zelenetz, Tarun Kewalramani, Jing Qin, Jaya M Satagopan, David Verbel, Ariela Noy, Carol S Portlock, David J Straus, Joachim Yahalom,…

  Source: Blood. 2003 Sep 15

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• Absence of a telomere maintenance mechanism as a favorable prognostic factor in patients with osteosarcoma.

  There are two telomere maintenance mechanisms (TMMs) in human tumors, telomerase activation (TA) and, more rarely, the process termed alternative leng…

  Authors: Gary A Ulaner, Hsuan-Ying Huang, Jesse Otero, Zhiquan Zhao, Leah Ben-Porat, Jaya M Satagopan, Richard Gorlick, Paul Meyers, John H Healey, Andrew G Huvos,…

  Source: Cancer research. 2003 Apr 15

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• Optimal two-stage genotyping in population-based association studies.

  We propose a cost-effective two-stage approach to investigate gene-disease associations when testing a large number of candidate markers using a case-…

  Authors: Jaya M Satagopan, Robert C Elston

  Source: Genetic epidemiology. 2003 Sep

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• Normalization method for transcriptional studies of heterogeneous samples--simultaneous array normalization and identification of equivalent expression.

  Normalization is an important step in the analysis of microarray data of transcription profiles as systematic non-biological variations often arise fr…

  Authors: Li-Xuan Qin, Jaya M Satagopan

  Source: Statistical applications in genetics and molecular biology. 2009 Jan

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• Two-stage designs for gene-disease association studies with sample size constraints.

  Gene-disease association studies based on case-control designs may often be used to identify candidate polymorphisms (markers) conferring disease risk…

  Authors: Jaya M Satagopan, E S Venkatraman, Colin B Begg

  Source: Biometrics. 2004 Sep

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