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CONTEXT: Variceal bleeding is the most frequent severe complication of portal hypertension and a leading cause of death and liver transplantation in p…
Authors: Jaume Bosch, Juan Carlos García-Pagán
Source: Lancet. 2003 Mar 15
View Full TextBACKGROUND & AIMS: Increased hepatic vascular resistance in cirrhosis is in part due to reduced nitric oxide (NO) bioavailability. This is related to …
Authors: Jorge Gracia-Sancho, Bàrbara Laviña, Aina Rodríguez-Vilarrupla, Ralf P Brandes, Mercedes Fernández, Jaume Bosch, Joan-Carles García-Pagán
Source: Gastroenterology. 2007 Sep
View Full TextAngiogenesis and disruption of liver vascular architecture have been linked to progression to cirrhosis and liver cancer (HCC) in chronic liver diseas…
Authors: Mercedes Fernández, David Semela, Jordi Bruix, Isabelle Colle, Massimo Pinzani, Jaume Bosch
Source: Journal of hepatology. 2009 Mar
View Full TextBACKGROUND & AIMS: Budd-Chiari syndrome (BCS) is a rare and life-threatening disorder secondary to hepatic venous outflow obstruction. Small series of…
Authors: Juan Carlos Garcia-Pagán, Mathis Heydtmann, Sebastian Raffa, Aurélie Plessier, Sarwa Murad, Federica Fabris, Giovanni Vizzini, Juan Gonzales Abraldes, Simon Olliff, Antonio Nicolini,…
Source: Gastroenterology. 2008 Sep
View Full TextBACKGROUND/AIMS: Cirrhotic patients chronically treated with beta-blockers who achieve a decrease of hepatic venous pressure gradient (HVPG) > or =20%…
Authors: Vincenzo La Mura, Juan G Abraldes, Sebastian Raffa, Oswaldo Retto, Annalisa Berzigotti, Juan Carlos García-Pagán, Jaume Bosch
Source: Journal of hepatology. 2009 Aug
View Full TextBACKGROUND/AIMS: The venous system is the primary capacitance region in the body. However, the influence of active changes in the venous system on the…
Authors: Victoria Andreu, Juan-Carlos Garcia-Pagan, Raffaela Lionetti, Carlos Piera, Juan G Abraldes, Jaume Bosch
Source: Journal of hepatology. 2006 Jun
View Full TextBACKGROUND & AIMS: A 50% dysfunction rate at 1 year is one of the main drawbacks of the transjugular intrahepatic portosystemic shunt procedure. Preli…
Authors: Christophe Bureau, Juan Carlos Garcia-Pagan, Philippe Otal, Gilles Pomier-Layrargues, Valérie Chabbert, Carlos Cortez, Pierre Perreault, Jean Marie Péron, Juan G Abraldes, Louis Bouchard,…
Source: Gastroenterology. 2004 Feb
View Full TextHuman growth hormone (hGH) is a protein endogenously produced predominantly by the anterior pituitary gland. Native hGH and, especially, its recombina…
Authors: Jordi Segura, Ricardo Gutiérrez-Gallego, Rosa Ventura, Josep A Pascual, Jaume Bosch, Gerard Such-Sanmartín, Zoran Nikolovski, Armand Pinyot, Simona Pichini
Source: Therapeutic drug monitoring. 2009 Feb
View Full TextBACKGROUND/AIMS: Albumin administration prevents renal failure and improves survival in spontaneous bacterial peritonitis. This study characterizes th…
Authors: Javier Fernández, Miguel Navasa, Juan Carlos Garcia-Pagan, Juan G-Abraldes, Wladimiro Jiménez, Jaume Bosch, Vicente Arroyo
Source: Journal of hepatology. 2004 Sep
View Full TextBACKGROUND/AIMS: Cirrhotic livers exhibit endothelial dysfunction that contributes to the increased hepatic vascular resistance. The present study eva…
Authors: Mariona Graupera, Joan-Carles García-Pagán, Mireia Parés, Juan G Abraldes, Joan Roselló, Jaume Bosch, Juan Rodés
Source: Journal of hepatology. 2003 Oct
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