1 to 8 of 8 literature results

• Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance.

  Chronic infection with hepatitis C virus (HCV) affects 170 million people worldwide and is the leading cause of cirrhosis in North America. Although t…

  Authors: Dongliang Ge, Jacques Fellay, Alexander J Thompson, Jason S Simon, Kevin V Shianna, Thomas J Urban, Erin L Heinzen, Ping Qiu, Arthur H Bertelsen, Andrew J Muir,…

  Source: Nature. 2009 Sep 17

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• Identification of single nucleotide polymorphisms of the human metabotropic glutamate receptor 1 gene and pharmacological characterization of a P993S variant.

  mGluR1 receptors are believed to play major roles in the pathophysiology of diseases such as anxiety and chronic pain and are being actively investiga…

  Authors: Patrick M Downey, Roberta Petrò, Jason S Simon, David Devlin, Gianluca Lozza, Alessio Veltri, Massimiliano Beltramo, Rosalia Bertorelli, Angelo Reggiani

  Source: Biochemical pharmacology. 2009 Apr 1

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• P518/Qrfp sequence polymorphisms in SAMP6 osteopenic mouse.

  Mice lacking GPR103A expression display osteopenia. Analysis of mouse quantitative trait loci literature associated with bone mineral density suggeste…

  Authors: Qing Zhang, Ping Qiu, M Gladys Arreaza, Jason S Simon, Andrei Golovko, Maureen Laverty, Galya Vassileva, Eric L Gustafson, Alberto Rojas-Triana, Loretta A Bober,…

  Source: Genomics. 2007 Nov

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• Sequence variation in NPC1L1 and association with improved LDL-cholesterol lowering in response to ezetimibe treatment.

  Niemann-Pick C1-like 1 (NPC1L1) is an intestinal cholesterol transporter and the molecular target of ezetimibe, a cholesterol absorption inhibitor dem…

  Authors: Jason S Simon, Maha C Karnoub, David J Devlin, Maria G Arreaza, Ping Qiu, Stephanie A Monks, Michael E Severino, Paul Deutsch, Joanne Palmisano, Alan B Sachs,…

  Source: Genomics. 2005 Dec

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• Identification and characterization of single-nucleotide polymorphisms in MCH-R1 and MCH-R2.

  OBJECTIVE: To identify and functionally characterize single-nucleotide polymorphisms (SNPs) in melanin-concentrating hormone (MCH)-R1 and -R2. RESEARC…

  Authors: Brian E Hawes, Beverly Green, Kim O'Neill, Steve Fried, M Gladys Arreaza, Ping Qiu, Jason S Simon

  Source: Obesity research. 2004 Aug

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• Genome wide in silico SNP-tumor association analysis.

  BACKGROUND: Carcinogenesis occurs, at least in part, due to the accumulation of mutations in critical genes that control the mechanisms of cell prolif…

  Authors: Ping Qiu, Luquan Wang, Mitch Kostich, Wei Ding, Jason S Simon, Jonathan R Greene

  Source: BMC cancer. 2004 Jan 29

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• Expression of the chemokine receptor CCR5 in psoriasis and results of a randomized placebo controlled trial with a CCR5 inhibitor.

  Several reports have indicated that the chemokine receptor CCR5 and its ligands, especially CCL5 (formerly known as RANTES), may play a role in the pa…

  Authors: Marjan de Groot, Marcel B M Teunissen, Jean P Ortonne, Julien R Lambert, Jean M Naeyaert, Daisy I Picavet, M Gladys Arreaza, Jason S Simon, Maarten Kraan, Jan D Bos,…

  Source: Archives of dermatological research. 2007 Sep

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• Cytogenetic and molecular characterization of A2BP1/FOX1 as a candidate gene for autism.

  Cytogenetic imbalances are increasingly being realized as causes of autism. Here, we report a de novo translocation between the short arms of chromoso…

  Authors: Christa Lese Martin, Jacqueline A Duvall, Yesim Ilkin, Jason S Simon, M Gladys Arreaza, Kristin Wilkes, Ana Alvarez-Retuerto, Amy Whichello, Cynthia M Powell, Kathleen Rao,…

  Source: American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. 2007 Oct 5

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