1 to 8 of 8 literature results

• The interval between Ins2 and Ascl2 is dispensable for imprinting centre function in the murine Beckwith-Wiedemann region.

  Imprinted genes are commonly clustered in domains across the mammalian genome, suggesting a degree of coregulation via long-range coordination of thei…

  Authors: Louis Lefebvre, Lynn Mar, Aaron Bogutz, Rosemary Oh-McGinnis, Mohammad A Mandegar, Jana Paderova, Marina Gertsenstein, Jeremy A Squire, Andras Nagy

  Source: Human molecular genetics. 2009 Nov 15

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• Epigenetic and phenotypic consequences of a truncation disrupting the imprinted domain on distal mouse chromosome 7.

  The distal end of mouse chromosome 7 (Chr 7) contains a large cluster of imprinted genes. In this region two cis-acting imprinting centers, IC1 (H19 D…

  Authors: Rosemary Oh, Rita Ho, Lynn Mar, Marina Gertsenstein, Jana Paderova, John Hsien, Jeremy A Squire, Michael J Higgins, Andras Nagy, Louis Lefebvre

  Source: Molecular and cellular biology. 2008 Feb

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• Murine Pif1 interacts with telomerase and is dispensable for telomere function in vivo.

  Pif1 is a 5'-to-3' DNA helicase critical to DNA replication and telomere length maintenance in the budding yeast Saccharomyces cerevisiae. ScPif1 is a…

  Authors: Bryan E Snow, Maria Mateyak, Jana Paderova, Andrew Wakeham, Caterina Iorio, Virginia Zakian, Jeremy Squire, Lea Harrington

  Source: Molecular and cellular biology. 2007 Feb

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• Novel 6p rearrangements and recurrent translocation breakpoints in retinoblastoma cell lines identified by spectral karyotyping and mBAND analyses.

  Gain of the short arm of chromosome 6, usually through isochromosome 6p formation, is present in approximately 50% of retinoblastoma tumors. The minim…

  Authors: Jana Paderova, Marija Orlic-Milacic, Maisa Yoshimoto, Gilda da Cunha Santos, Brenda Gallie, Jeremy A Squire

  Source: Cancer genetics and cytogenetics. 2007 Dec

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• The breakage-fusion-bridge (BFB) cycle as a mechanism for generating genetic heterogeneity in osteosarcoma.

  Osteosarcoma (OS) is characterized by chromosomal instability and high copy number gene amplification. The breakage-fusion-bridge (BFB) cycle is a wel…

  Authors: Shamini Selvarajah, Maisa Yoshimoto, Paul C Park, Georges Maire, Jana Paderova, Jane Bayani, Gloria Lim, Khaldoun Al-Romaih, Jeremy A Squire, Maria Zielenska

  Source: Chromosoma. 2006 Dec

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• Identification of cryptic microaberrations in osteosarcoma by high-definition oligonucleotide array comparative genomic hybridization.

  Osteosarcoma (OS) is an aggressive bone tumor characterized by complex abnormal karyotypes and a high level of genomic instability. Using high-resolut…

  Authors: Shamini Selvarajah, Maisa Yoshimoto, Georges Maire, Jana Paderova, Jane Bayani, Jeremy A Squire, Maria Zielenska

  Source: Cancer genetics and cytogenetics. 2007 Nov

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• Distinct patterns of structural and numerical chromosomal instability characterize sporadic ovarian cancer.

  Sporadic ovarian cancer is a particularly aggressive tumor characterized by highly abnormal karyotypes exhibiting many features of genomic instability…

  Authors: Jane Bayani, Jana Paderova, Joan Murphy, Barry Rosen, Maria Zielenska, Jeremy A Squire

  Source: Neoplasia (New York, N.Y.). 2008 Oct

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• High definition cytogenetics and oligonucleotide aCGH analyses of cisplatin-resistant ovarian cancer cells.

  Array comparative genomic hybridization (aCGH) is a key platform to assess cancer genomic profiles. Many structural genomic aberrations cannot be dete…

  Authors: Mona Prasad, Marcus Bernardini, Anya Tsalenko, Paula Marrano, Jana Paderova, Chung-Hae Lee, Amir Ben-Dor, Michael T Barrett, Jeremy A Squire

  Source: Genes, chromosomes & cancer. 2008 May

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