1 to 10 of 14,819 literature results

• Evidence for escape from adaptive conflict?

  Gene duplication is the primary source of new genes, but the molecular evolutionary mechanisms underlying functional divergence of duplicate genes are…

  Authors: Todd Barkman, Jianzhi Zhang

  Source: Nature. 2009 Dec 10

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• Parallel adaptive origins of digestive RNases in Asian and African leaf monkeys.

  Similar morphological or physiological changes occurring in multiple evolutionary lineages are not uncommon. Such parallel changes are believed to be …

  Authors: Jianzhi Zhang

  Source: Nature genetics. 2006 Jul

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• Essential roles of PI(3)K-p110beta in cell growth, metabolism and tumorigenesis.

  On activation by receptors, the ubiquitously expressed class IA isoforms (p110alpha and p110beta) of phosphatidylinositol-3-OH kinase (PI(3)K) generat…

  Authors: Shidong Jia, Zhenning Liu, Sen Zhang, Pixu Liu, Lei Zhang, Sang Hyun Lee, Jing Zhang, Sabina Signoretti, Massimo Loda, Thomas M Roberts,…

  Source: Nature. 2008 Aug 7

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• MicroRNAs to Nanog, Oct4 and Sox2 coding regions modulate embryonic stem cell differentiation.

  MicroRNAs (miRNAs) are short RNAs that direct messenger RNA degradation or disrupt mRNA translation in a sequence-dependent manner. For more than a de…

  Authors: Yvonne Tay, Jinqiu Zhang, Andrew M Thomson, Bing Lim, Isidore Rigoutsos

  Source: Nature. 2008 Oct 23

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• Neurotoxic autoantibodies mediate congenital cortical impairment of offspring in maternal lupus.

  Systemic lupus erythematosus (SLE) is an autoimmune disease mediated by autoantibodies and preferentially affecting women of childbearing age. Because…

  Authors: Ji Y Lee, Patricio T Huerta, Jie Zhang, Czeslawa Kowal, Eva Bertini, Bruce T Volpe, Betty Diamond

  Source: Nature medicine. 2009 Jan

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• Prevalent positive epistasis in Escherichia coli and Saccharomyces cerevisiae metabolic networks.

  Epistasis refers to the interaction between genes. Although high-throughput epistasis data from model organisms are being generated and used to constr…

  Authors: Xionglei He, Wenfeng Qian, Zhi Wang, Ying Li, Jianzhi Zhang

  Source: Nature genetics. 2010 Mar

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• Structural basis for the photoconversion of a phytochrome to the activated Pfr form.

  Phytochromes are a collection of bilin-containing photoreceptors that regulate numerous photoresponses in plants and microorganisms through their abil…

  Authors: Andrew T Ulijasz, Gabriel Cornilescu, Claudia C Cornilescu, Junrui Zhang, Mario Rivera, John L Markley, Richard D Vierstra

  Source: Nature. 2010 Jan 14

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• Coexistence of Fermi arcs and Fermi pockets in a high-T(c) copper oxide superconductor.

  In the pseudogap state of the high-transition-temperature (high-T(c)) copper oxide superconductors, angle-resolved photoemission (ARPES) measurements …

  Authors: Jianqiao Meng, Guodong Liu, Wentao Zhang, Lin Zhao, Haiyun Liu, Xiaowen Jia, Daixiang Mu, Shanyu Liu, Xiaoli Dong, Jun Zhang,…

  Source: Nature. 2009 Nov 19

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• Structural basis for substrate loading in bacterial RNA polymerase.

  The mechanism of substrate loading in multisubunit RNA polymerase is crucial for understanding the general principles of transcription yet remains hot…

  Authors: Dmitry G Vassylyev, Marina N Vassylyeva, Jinwei Zhang, Murali Palangat, Irina Artsimovitch, Robert Landick

  Source: Nature. 2007 Jul 12

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• Constant darkness is a circadian metabolic signal in mammals.

  Environmental light is the 'zeitgeber' (time-giver) of circadian behaviour. Constant darkness is considered a 'free-running' circadian state. Mammals …

  Authors: Jianfa Zhang, Krista Kaasik, Michael R Blackburn, Cheng Chi Lee

  Source: Nature. 2006 Jan 19

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