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Insulin modulates gluconeogenesis by inhibition of the coactivator TORC2.
During feeding, increases in circulating pancreatic insulin inhibit hepatic glucose output through the activation of the Ser/Thr kinase AKT and subseq…
Authors: Renaud Dentin, Yi Liu, Seung-Hoi Koo, Susan Hedrick, Thomas Vargas, Jose Heredia, John Yates, Marc Montminy
Source: Nature. 2007 Sep 20
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Localized release of serotonin (5-hydroxytryptamine) by a fecal pellet regulates migrating motor complexes in murine colon.
BACKGROUND & AIMS: The colonic migrating motor complex (CMMC) is a motor pattern that regulates the movement of fecal matter through a rhythmic sequen…
Authors: Dante J Heredia, Eamonn J Dickson, Peter O Bayguinov, Grant W Hennig, Terence K Smith
Source: Gastroenterology. 2009 Apr
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An enteric occult reflex underlies accommodation and slow transit in the distal large bowel.
BACKGROUND & AIMS: Transit of fecal material through the human colon takes > or =30 hours, whereas transit through the small intestine takes 24 hours.…
Authors: Eamonn J Dickson, Nick J Spencer, Grant W Hennig, Peter O Bayguinov, Jim Ren, Dante J Heredia, Terence K Smith
Source: Gastroenterology. 2007 May
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Improvement of postural adjustment steps in hemiparkinsonian rats chronically treated with caffeine is mediated by concurrent blockade of A1 and A2A adenosine receptors.
Chronic treatment with the non-selective adenosine receptor antagonist caffeine produces full recovery of the contralateral adjusting steps in hemipar…
Authors: José L Bata-García, Luis Tun-Cobá, Fernando J Alvarez-Cervera, Jairo R Villanueva-Toledo, Francisco J Heredia-López, José L Góngora-Alfaro
Source: Neuroscience. 2010 Jan 4
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Synthesis of beta-(S-methyl)thioaspartic acid and derivatives.
Beta-(S-Methyl)thioaspartic acid occurs as a posttranslational modification at position 88 in Escherichia coli ribosomal protein S12, a position that …
Authors: Jorge Heredia-Moya, Kenneth L Kirk
Source: Bioorganic & medicinal chemistry. 2008 Jun 1
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An improved synthesis of arsenic-biotin conjugates.
An amide linked conjugate of p-aminophenylarsine oxide and biotin is conveniently prepared in a one-pot procedure by the reaction of biotinyl chloride…
Authors: Jorge Heredia-Moya, Kenneth L Kirk
Source: Bioorganic & medicinal chemistry. 2008 May 15
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In Vitro Double Transposition for DNA Identification.
A double transposition technique is presented that inserts two different transposons into target DNA to act as priming sites for amplifying the region…
Authors: Nicholas J Heredia, N Reginald Beer, Christine A Hara, Amy L Hiddessen, Christopher G Bailey
Source: Analytical biochemistry. 2009 Nov 24
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Separation of structural, geometrical and optical isomers of epoxycarotenoids using triacontyl-bonded stationary phases.
The efficiency of C30 stationary phases in the separation of carotenes and diverse hydroxycarotenoids has been the subject of several studies. However…
Authors: Antonio J Meléndez-Martínez, Maria L Escudero-Gilete, Isabel M Vicario, Francisco J Heredia
Source: Journal of separation science. 2009 Jun
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Rapid assessment of vitamin A activity through objective color measurements for the quality control of orange juices with diverse carotenoid profiles.
The evaluation of the vitamin A activity of foods is important for the establishment of Dietary Reference Intakes and food composition databases, food…
Authors: Antonio J Meléndez-Martínez, Isabel M Vicario, Francisco J Heredia
Source: Journal of agricultural and food chemistry. 2007 Apr 18
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Carotenoids, color, and ascorbic acid content of a novel frozen-marketed orange juice.
A recently developed food, the so-called ultrafrozen orange juice (UFOJ), has been characterized in terms of carotenoid pigments, ascorbic acid, and c…
Authors: Antonio J Meléndez-Martínez, Isabel M Vicario, Francisco J Heredia
Source: Journal of agricultural and food chemistry. 2007 Feb 21
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