1 to 10 of 15,553 literature results

• The Immunobiology of SARS*.

  Severe acute respiratory syndrome (SARS) presented as an atypical pneumonia that progressed to acute respiratory distress syndrome in approximately 20…

  Authors: Jun Chen, Kanta Subbarao

  Source: Annual review of immunology. 2007

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• The role of ubiquitin in NF-kappaB regulatory pathways.

  Nuclear factor kappa enhancer binding protein (NF-kappaB) regulates diverse biological processes including immunity, inflammation, and apoptosis. A va…

  Authors: Brian Skaug, Xiaomo Jiang, Zhijian J Chen

  Source: Annual review of biochemistry. 2009

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• Ubiquitylation in innate and adaptive immunity.

  Protein ubiquitylation has emerged as a key mechanism that regulates immune responses. Much like phosphorylation, ubiquitylation is a reversible coval…

  Authors: Vijay G Bhoj, Zhijian J Chen

  Source: Nature. 2009 Mar 26

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• DBC1 is a negative regulator of SIRT1.

  The NAD-dependent protein deacetylase Sir2 (silent information regulator 2) regulates lifespan in several organisms. SIRT1, the mammalian orthologue o…

  Authors: Ja-Eun Kim, Junjie Chen, Zhenkun Lou

  Source: Nature. 2008 Jan 31

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• Runx1 is required for the endothelial to haematopoietic cell transition but not thereafter.

  Haematopoietic stem cells (HSCs) are the founder cells of the adult haematopoietic system, and thus knowledge of the molecular program directing their…

  Authors: Michael J Chen, Tomomasa Yokomizo, Brandon M Zeigler, Elaine Dzierzak, Nancy A Speck

  Source: Nature. 2009 Feb 12

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• Protein kinase DYRK2 is a scaffold that facilitates assembly of an E3 ligase.

  Protein kinases have central functions in various cellular signal transduction pathways through their substrate phosphorylation. Here we show that a p…

  Authors: Subbareddy Maddika, Junjie Chen

  Source: Nature cell biology. 2009 Apr

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• Linking retroelements to autoimmunity.

  In this issue, Stetson et al. (2008) report a mechanism by which host cells avert an autoimmune response to self-nucleic acids. They show that the nuc…

  Authors: Vijay G Bhoj, Zhijian J Chen

  Source: Cell. 2008 Aug 22

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• Development of novel conjugated donor polymers for high-efficiency bulk-heterojunction photovoltaic devices.

  Solar cells are one attractive method for harnessing inexhaustible clean energy from the sun. Organic photovoltaic technology is emerging as a potenti…

  Authors: Junwu Chen, Yong Cao

  Source: Accounts of chemical research. 2009 Nov 17

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• Nonproteolytic functions of ubiquitin in cell signaling.

  The small protein ubiquitin is a central regulator of a cell's life and death. Ubiquitin is best known for targeting protein destruction by the 26S pr…

  Authors: Zhijian J Chen, Lijun J Sun

  Source: Molecular cell. 2009 Feb 13

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• Quasicrystalline order in self-assembled binary nanoparticle superlattices.

  The discovery of quasicrystals in 1984 changed our view of ordered solids as periodic structures and introduced new long-range-ordered phases lacking …

  Authors: Dmitri V Talapin, Elena V Shevchenko, Maryna I Bodnarchuk, Xingchen Ye, Jun Chen, Christopher B Murray

  Source: Nature. 2009 Oct 15

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