1 to 10 of 14 literature results

• Reconstituted NALP1 inflammasome reveals two-step mechanism of caspase-1 activation.

  Interleukin (IL)-1beta maturation is accomplished by caspase-1-mediated proteolysis, an essential element of innate immunity. NLRs constitute a recent…

  Authors: Benjamin Faustin, Lydia Lartigue, Jean-Marie Bruey, Frederic Luciano, Eduard Sergienko, Beatrice Bailly-Maitre, Niels Volkmann, Dorit Hanein, Isabelle Rouiller, John C Reed

  Source: Molecular cell. 2007 Mar 9

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• Breathing" vesicles.

  A vesicle system is described that possesses a pH-induced "breathing" feature and consists of a three-layered wall structure. The "breathing" feature …

  Authors: Shaoyong Yu, Tony Azzam, Isabelle Rouiller, Adi Eisenberg

  Source: Journal of the American Chemical Society. 2009 Aug 5

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• Hereditary inclusion body myopathy-linked p97/VCP mutations in the NH2 domain and the D1 ring modulate p97/VCP ATPase activity and D2 ring conformation.

  Hereditary inclusion body myopathy associated with early-onset Paget disease of bone and frontotemporal dementia (hIBMPFTD) is a degenerative disorder…

  Authors: Dalia Halawani, Andréa C LeBlanc, Isabelle Rouiller, Stephen W Michnick, Marc J Servant, Martin Latterich

  Source: Molecular and cellular biology. 2009 Aug

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• The subcellular distribution of multigene family 110 proteins of African swine fever virus is determined by differences in C-terminal KDEL endoplasmic reticulum retention motifs.

  African swine fever virus (ASFV) is a large double-stranded DNA virus that replicates in discrete areas in the cytosol of infected cells called viral …

  Authors: Christopher Netherton, Isabelle Rouiller, Thomas Wileman

  Source: Journal of virology. 2004 Apr

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• Role of capsid sequence and immature nucleocapsid proteins p9 and p15 in Human Immunodeficiency Virus type 1 genomic RNA dimerization.

  HIV-1 genomic RNA (gRNA) dimerization is important for viral infectivity and is regulated by proteolytic processing of the Gag precursor protein (Pr55…

  Authors: Jafar Kafaie, Marjan Dolatshahi, Lara Ajamian, Rujun Song, Andrew J Mouland, Isabelle Rouiller, Michael Laughrea

  Source: Virology. 2009 Mar 1

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• Conformational changes of the multifunction p97 AAA ATPase during its ATPase cycle.

  p97 (also called VCP), a member of the AAA ATPase family, is involved in several cellular processes, including membrane fusion and extraction of prote…

  Authors: Isabelle Rouiller, Byron DeLaBarre, Andrew P May, William I Weis, Axel T Brunger, Ronald A Milligan, Elizabeth M Wilson-Kubalek

  Source: Nature structural biology. 2002 Dec

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• Prepore to pore transition of a cholesterol-dependent cytolysin visualized by electron microscopy.

  Perfringolysin O (PFO), a soluble toxin secreted by the pathogenic Clostridium perfringens, forms large homo-oligomeric pore complexes comprising up t…

  Authors: Thanh X Dang, Eileen M Hotze, Isabelle Rouiller, Rodney K Tweten, Elizabeth M Wilson-Kubalek

  Source: Journal of structural biology. 2005 Apr

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• Model-based particle picking for cryo-electron microscopy.

  We describe an algorithm for finding particle images in cryo-EM micrographs. The algorithm starts from a crude 3D map of the target particle, computed…

  Authors: H Chi Wong, Jindong Chen, Fabrice Mouche, Isabelle Rouiller, Marshall Bern

  Source: Journal of structural biology. 2004 Jan-Feb

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• Supported bilayers formed from different phospholipids on spherical silica substrates.

  Spherical supported bilayer membranes (SS-BLMs) are very attractive candidates in modern bioanalytics and biorecognition studies. A uniform, facile me…

  Authors: Gopakumar Gopalakrishnan, Isabelle Rouiller, David R Colman, R Bruce Lennox

  Source: Langmuir : the ACS journal of surfaces and colloids. 2009 May 19

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• Mechanistic differences in actin bundling activity of two mammalian formins, FRL1 and mDia2.

  Formin proteins are regulators of actin dynamics, mediating assembly of unbranched actin filaments. These multidomain proteins are defined by the pres…

  Authors: Elizabeth S Harris, Isabelle Rouiller, Dorit Hanein, Henry N Higgs

  Source: The Journal of biological chemistry. 2006 May 19

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