1 to 3 of 3 literature results

• Nuclear receptor ERR alpha and coactivator PGC-1 beta are effectors of IFN-gamma-induced host defense.

  Macrophage activation by the proinflammatory cytokine interferon-gamma (IFN-gamma) is a critical component of the host innate response to bacterial pa…

  Authors: Junichiro Sonoda, Josée Laganière, Isaac R Mehl, Grant D Barish, Ling-Wa Chong, Xiangli Li, Immo E Scheffler, Dennis C Mock, Alain R Bataille, Francois Robert,…

  Source: Genes & development. 2007 Aug 1

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• PGC-1beta controls mitochondrial metabolism to modulate circadian activity, adaptive thermogenesis, and hepatic steatosis.

  The transcriptional coactivator peroxisome proliferator-activated receptor-gamma coactivator 1beta (PGC-1beta) is believed to control mitochondrial ox…

  Authors: Junichiro Sonoda, Isaac R Mehl, Ling-Wa Chong, Russell R Nofsinger, Ronald M Evans

  Source: Proceedings of the National Academy of Sciences of the United States of America. 2007 Mar 20

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• Peroxisome proliferator-activated receptor delta promotes very low-density lipoprotein-derived fatty acid catabolism in the macrophage.

  Significant attention has focused on the role of low-density lipoprotein (LDL) in the pathogenesis of atherosclerosis. However, recent advances have i…

  Authors: Chih-Hao Lee, Kihwa Kang, Isaac R Mehl, Russell Nofsinger, William A Alaynick, Ling-Wa Chong, John M Rosenfeld, Ronald M Evans

  Source: Proceedings of the National Academy of Sciences of the United States of America. 2006 Feb 14

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