1 to 8 of 8 literature results

• KChIP2 attenuates cardiac hypertrophy through regulation of Ito and intracellular calcium signaling.

  Recent evidence shows that the auxiliary subunit KChIP2, which assembles with pore-forming Kv4-subunits, represents a new potential regulator of the c…

  Authors: Hongwei Jin, Lahouaria Hadri, Julieta Palomeque, Charlotte Morel, Ioannis Karakikes, Roger Kaprielian, Roger Hajjar, Djamel Lebeche

  Source: Journal of molecular and cellular cardiology. 2010 Jun

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• Detecting and quantifying colocalization of cell surface molecules by single particle fluorescence imaging.

  Single particle fluorescence imaging (SPFI) uses the high sensitivity of fluorescence to visualize individual molecules that have been selectively lab…

  Authors: Ian E G Morrison, Ioannis Karakikes, Rosamund E Barber, Nelson Fernández, Richard J Cherry

  Source: Biophysical journal. 2003 Dec

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• Gene remodeling in type 2 diabetic cardiomyopathy and its phenotypic rescue with SERCA2a.

  BACKGROUND/AIM: Diabetes-associated myocardial dysfunction results in altered gene expression in the heart. We aimed to investigate the changes in gen…

  Authors: Ioannis Karakikes, Maengjo Kim, Lahouaria Hadri, Susumu Sakata, Yezhou Sun, Weijia Zhang, Elie R Chemaly, Roger J Hajjar, Djamel Lebeche

  Source: PloS one. 2009

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• Growth-factor-mediated cardiac stem cell activation in myocardial regeneration.

  The concept of an intrinsic regenerative capacity of the adult mammalian myocardium owing to the presence of cardiac stem cells (CSCs) in the atria an…

  Authors: Daniele Torella, Georgina M Ellison, Ioannis Karakikes, Bernardo Nadal-Ginard

  Source: Nature clinical practice. Cardiovascular medicine. 2007 Feb

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• Myocyte death and renewal: modern concepts of cardiac cellular homeostasis.

  The adult mammalian myocardium has a robust intrinsic regenerative capacity because of the presence of cardiac stem cells (CSCs). Despite being mainly…

  Authors: Georgina M Ellison, Daniele Torella, Ioannis Karakikes, Bernardo Nadal-Ginard

  Source: Nature clinical practice. Cardiovascular medicine. 2007 Feb

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• Mechanical work and energetic analysis of eccentric cardiac remodeling in a volume overload heart failure in rats.

  Eccentric cardiac remodeling seen in dilated cardiomyopathy or regurgitant valvular disease is a well-known process of heart failure progression, but …

  Authors: Yoshiaki Takewa, Elie R Chemaly, Miyako Takaki, Li Fan Liang, Hongwei Jin, Ioannis Karakikes, Charlotte Morel, Yoshiyuki Taenaka, Eisuke Tatsumi, Roger J Hajjar

  Source: American journal of physiology. Heart and circulatory physiology. 2009 Apr

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• Gene Delivery of Sarcoplasmic Reticulum Calcium ATPase Inhibits Ventricular Remodeling in Ischemic Mitral Regurgitation.

  BACKGROUND: -Mitral regurgitation (MR) doubles mortality following myocardial infarction (MI). We have demonstrated that MR worsens remodeling after M…

  Authors: Ronen Beeri, Miguel Chaput, J Luis Guerrero, Yoshiaki Kawase, Chaim Yosefy, Suzan Abedat, Ioannis Karakikes, Charlotte Morel, Ashley Tisosky, Suzanne Sullivan,…

  Source: Circulation. Heart failure. 2010 Jul 15

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• Acute beta-adrenergic overload produces myocyte damage through calcium leakage from the ryanodine receptor 2 but spares cardiac stem cells.

  A hyperadrenergic state is a seminal aspect of chronic heart failure. Also, "Takotsubo stress cardiomyopathy," is associated with increased plasma cat…

  Authors: Georgina M Ellison, Daniele Torella, Ioannis Karakikes, Saranya Purushothaman, Antonio Curcio, Cosimo Gasparri, Ciro Indolfi, N Tim Cable, David F Goldspink, Bernardo Nadal-Ginard

  Source: The Journal of biological chemistry. 2007 Apr 13

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