1 to 8 of 8 literature results

• Coactivating factors p300 and CBP are transcriptionally crossregulated by Egr1 in prostate cells, leading to divergent responses.

  Related coactivators p300 and CBP affect the transcriptional activities of many transcription factors (TF), producing multiple downstream effects. Her…

  Authors: Jianxiu Yu, Ian de Belle, Hongyan Liang, Eileen D Adamson

  Source: Molecular cell. 2004 Jul 2

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• TOE1 interacts with p53 to modulate its transactivation potential.

  The TOE1 gene was discovered as a target of the Egr1 transcription factor that participates in cell growth regulation through the upregulation of p21 …

  Authors: Sabina Sperandio, Saverio Tardito, Aleksandra Surzycki, Martin Latterich, Ian de Belle

  Source: FEBS letters. 2009 Jul 7

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• Daxx represses expression of a subset of antiapoptotic genes regulated by nuclear factor-kappaB.

  Daxx is a nuclear protein that localizes to PML oncogenic domains, sensitizes cells to apoptosis, and functions as a transcriptional repressor. We fou…

  Authors: Rhonda Croxton, Lorena A Puto, Ian de Belle, Michael Thomas, Seiji Torii, Farid Hanaii, Michael Cuddy, John C Reed

  Source: Cancer research. 2006 Sep 15

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• The transcription factor Egr1 regulates the HIF-1alpha gene during hypoxia.

  Using oligonucleotide expression microarrays we have examined the modulation of gene expression in the DU145 prostate cancer cell line. Our findings c…

  Authors: Sabina Sperandio, Jessyka Fortin, Roman Sasik, Lynda Robitaille, Jacques Corbeil, Ian de Belle

  Source: Molecular carcinogenesis. 2009 Jan

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• Egr1 signaling in prostate cancer.

  Egr1 is a multifunctional transcription factor regulating a remarkable spectrum of cellular responses from survival to apoptosis, growth to growth arr…

  Authors: Eileen Adamson, Ian de Belle, Shalu Mittal, Yipeng Wang, Jun Hayakawa, Kemal Korkmaz, David O'Hagan, Michael McClelland, Dan Mercola

  Source: Cancer biology & therapy. 2003 Nov-Dec

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• Promoter array" studies identify cohorts of genes directly regulated by methylation, copy number change, or transcription factor binding in human cancer cells.

  DNA microarrays of promoter sequences have been developed in order to identify the profile of genes bound and activated by DNA regulatory proteins suc…

  Authors: Yipeng Wang, Jun Hayakawa, Fred Long, Qiuju Yu, Ann H Cho, Gaelle Rondeau, John Welsh, Shalu Mittal, Ian De Belle, Eileen Adamson,…

  Source: Annals of the New York Academy of Sciences. 2005 Nov

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• In vivo cloning and characterization of a new growth suppressor protein TOE1 as a direct target gene of Egr1.

  Egr1, an immediate early transcription factor, responds to diverse stimuli and affects gene transcription to accomplish its biological effects. One im…

  Authors: Ian De Belle, Jie-Xin Wu, Sabina Sperandio, Dan Mercola, Eileen D Adamson

  Source: The Journal of biological chemistry. 2003 Apr 18

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• Insulin-like growth factor-II regulates PTEN expression in the mammary gland.

  The tumor suppressor PTEN is altered in many cancers, including breast cancer, but only a handful of factors are known to control its expression. PTEN…

  Authors: Roger A Moorehead, Carlo V Hojilla, Ian De Belle, Geoffrey A Wood, Jimmie E Fata, Eileen D Adamson, Katrina L M Watson, Dylan R Edwards, Rama Khokha

  Source: The Journal of biological chemistry. 2003 Dec 12

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