1 to 10 of 21 literature results

• Rosiglitazone reduces the development and rupture of experimental aortic aneurysms.

  BACKGROUND: Development and rupture of aortic aneurysms involve a combination of complex biological processes. Rosiglitazone, a peroxisome proliferato…

  Authors: Alun Jones, Rajdeep Deb, Evelyn Torsney, Franklyn Howe, Mathew Dunkley, Yanosha Gnaneswaran, David Gaze, Hosaam Nasr, Ian M Loftus, Mathew M Thompson,…

  Source: Circulation. 2009 Jun 23

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• Hypoxia at the site of abdominal aortic aneurysm rupture is not associated with increased lactate.

  The mechanisms of hypoxia-mediated aneurysm wall weakening and rupture are unknown. During hypoxia, strategies to maintain cellular ATP levels include…

  Authors: Edward Choke, Gillian W Cockerill, Joseph Dawson, Yuen-Li Chung, John Griffiths, Richard W Wilson, Ian M Loftus, Matthew M Thompson

  Source: Annals of the New York Academy of Sciences. 2006 Nov

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• Gene expression profile of abdominal aortic aneurysm rupture.

  To search for novel transcriptional pathways that are activated in abdominal aortic aneurysm rupture, cDNA microarrays were used to compare global mRN…

  Authors: Edward Choke, Matthew M Thompson, Alun Jones, Evelyn Torsney, Joseph Dawson, Kenneth Laing, Hosaam Nasr, Ian M Loftus, Gillian W Cockerill

  Source: Annals of the New York Academy of Sciences. 2006 Nov

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• Increased angiogenesis at the site of abdominal aortic aneurysm rupture.

  Abdominal aortic aneurysm (AAA) rupture is associated with elevated levels of matrix metalloproteinase (MMP). Medial neovascularization is a known cha…

  Authors: Edward Choke, Gillian W Cockerill, Joseph Dawson, Richard W Wilson, Alun Jones, Ian M Loftus, Matthew M Thompson

  Source: Annals of the New York Academy of Sciences. 2006 Nov

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• Visceral and renal artery complications of suprarenal fixation during endovascular aneurysm repair.

  BACKGROUND: The effect of suprarenal fixation of endovascular grafts on renal and visceral artery function remains undefined. This study aimed to dete…

  Authors: Edward Choke, Graham Munneke, Robert Morgan, Anna-Maria Belli, Joseph Dawson, Ian M Loftus, Robert McFarland, Thomas Loosemore, Matthew M Thompson

  Source: Cardiovascular and interventional radiology. 2007 Jul-Aug

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• Plasma MMP-9 and MMP-2 following acute myocardial infarction in man: correlation with echocardiographic and neurohumoral parameters of left ventricular dysfunction.

  BACKGROUND: Left ventricular dilatation and elevated plasma natriuretic peptide levels predict adverse prognosis and the development of congestive hea…

  Authors: Iain B Squire, Jon Evans, Leong L Ng, Ian M Loftus, Matt M Thompson

  Source: Journal of cardiac failure. 2004 Aug

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• The role of carotid stenting.

  Despite a number of randomized trials, debate continues about the role of carotid angioplasty and stenting (CAS) for both symptomatic and asymptomatic…

  Authors: Ian M Loftus, Matthew M Thompson

  Source: Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists. 2007 Oct

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• Toward an "off-the-shelf" fenestrated endograft for management of short-necked abdominal aortic aneurysms: an analysis of current graft morphological diversity.

  PURPOSE: To examine the feasibility of an "off-the-shelf" fenestrated endograft repository to broaden the applicability of fenestrated endovascular an…

  Authors: Ian M Nordon, Robert J Hinchliffe, Brian Manning, Krassi Ivancev, Peter J Holt, Ian M Loftus, Matt M Thompson

  Source: Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists. 2010 Feb

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• Effect of endovascular aneurysm repair on the volume-outcome relationship in aneurysm repair.

  BACKGROUND: We aim to quantify the relationship between the annual caseload (volume) and outcome from elective endovascular (EVR) or open repair of ab…

  Authors: Peter J E Holt, Jan D Poloniecki, Usman Khalid, Robert J Hinchliffe, Ian M Loftus, Matt M Thompson

  Source: Circulation. Cardiovascular quality and outcomes. 2009 Nov

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• Evidence from cross-sectional imaging indicates abdominal but not thoracic aortic aneurysms are local manifestations of a systemic dilating diathesis.

  INTRODUCTION: The pathogenesis of aortic aneurysms remains unclear. There is epidemiologic and histologic evidence showing significant differences in …

  Authors: Ian Nordon, Ranjeet Brar, Jeremy Taylor, Robert Hinchliffe, Ian M Loftus, Matt M Thompson

  Source: Journal of vascular surgery : official publication, the Society for Vascular Surgery [and] International Society for Cardiovascular Surgery, North American Chapter. 2009 Jul

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