1 to 10 of 11 literature results

• The centrosomal protein nephrocystin-6 is mutated in Joubert syndrome and activates transcription factor ATF4.

  The molecular basis of nephronophthisis, the most frequent genetic cause of renal failure in children and young adults, and its association with retin…

  Authors: John A Sayer, Edgar A Otto, John F O'Toole, Gudrun Nurnberg, Michael A Kennedy, Christian Becker, Hans Christian Hennies, Juliana Helou, Massimo Attanasio, Blake V Fausett,…

  Source: Nature genetics. 2006 Jun

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• Molecular dynamics studies of polyethylene oxide and polyethylene glycol: hydrodynamic radius and shape anisotropy.

  A revision (C35r) to the CHARMM ether force field is shown to reproduce experimentally observed conformational populations of dimethoxyethane. Molecul…

  Authors: Hwankyu Lee, Richard M Venable, Alexander D Mackerell, Richard W Pastor

  Source: Biophysical journal. 2008 Aug

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• Molecular dynamics simulations of the anchoring and tilting of the lung-surfactant peptide SP-B1-25 in palmitic acid monolayers.

  We have performed molecular dynamics simulations of multiple copies of the lung-surfactant peptide SP-B1-25 in a palmitic acid (PA) monolayer. SP-B1-2…

  Authors: Hwankyu Lee, Senthil K Kandasamy, Ronald G Larson

  Source: Biophysical journal. 2005 Dec

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• Structure and dynamics of helix-0 of the N-BAR domain in lipid micelles and bilayers.

  Bin/Amphiphysin/Rvs-homology (BAR) domains generate and sense membrane curvature by binding the negatively charged membrane to their positively charge…

  Authors: Christian Löw, Ulrich Weininger, Hwankyu Lee, Kristian Schweimer, Ines Neundorf, Annette G Beck-Sickinger, Richard W Pastor, Jochen Balbach

  Source: Biophysical journal. 2008 Nov 1

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• Molecular dynamics study of the structure and interparticle interactions of polyethylene glycol-conjugated PAMAM dendrimers.

  We performed molecular dynamics (MD) simulations of one or two copies of polyethylene glycol of molecular weight 550 (PEG550) and 5000 (PEG5000) dalto…

  Authors: Hwankyu Lee, Ronald G Larson

  Source: The journal of physical chemistry. B. 2009 Oct 8

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• Coarse-grained molecular dynamics studies of the concentration and size dependence of fifth- and seventh-generation PAMAM dendrimers on pore formation in DMPC bilayer.

  We have performed molecular dynamics (MD) simulations of multiple copies of unacetylated G5 and G7 and acetylated G5 dendrimers in dimyristoylphosphat…

  Authors: Hwankyu Lee, Ronald G Larson

  Source: The journal of physical chemistry. B. 2008 Jul 3

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• Multiscale modeling of dendrimers and their interactions with bilayers and polyelectrolytes.

  Recent advances in molecular dynamics simulation methodologies and computational power have allowed accurate predictions of dendrimer size, shape, and…

  Authors: Hwankyu Lee, Ronald G Larson

  Source: Molecules (Basel, Switzerland). 2009

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• Lipid bilayer curvature and pore formation induced by charged linear polymers and dendrimers: the effect of molecular shape.

  We performed molecular dynamics (MD) simulations of multiple copies of poly- l-lysine (PLL) and charged polyamidoamine (PAMAM) dendrimers in dimyristo…

  Authors: Hwankyu Lee, Ronald G Larson

  Source: The journal of physical chemistry. B. 2008 Oct 2

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• Molecular dynamics simulations of PAMAM dendrimer-induced pore formation in DPPC bilayers with a coarse-grained model.

  We have performed 0.5-micros-long molecular dynamics (MD) simulations of 0%, 50%, and 100% acetylated third- (G3) and fifth-generation (G5) polyamidoa…

  Authors: Hwankyu Lee, Ronald G Larson

  Source: The journal of physical chemistry. B. 2006 Sep 21

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• A coarse-grained model for polyethylene oxide and polyethylene glycol: conformation and hydrodynamics.

  A coarse-grained (CG) model for polyethylene oxide (PEO) and polyethylene glycol (PEG) developed within the framework of the MARTINI CG force field (F…

  Authors: Hwankyu Lee, Alex H de Vries, Siewert-Jan Marrink, Richard W Pastor

  Source: The journal of physical chemistry. B. 2009 Oct 8

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