1 to 10 of 13 literature results

• Type III secretion translocation pores of Yersinia enterocolitica trigger maturation and release of pro-inflammatory IL-1beta.

  Bacteria from the genus Yersinia deliver a number of effectors into host cells via type III secretion (T3S). Injected Yop effectors interfere and prev…

  Authors: Hwain Shin, Guy R Cornelis

  Source: Cellular microbiology. 2007 Dec

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• Resistance of Capnocytophaga canimorsus to killing by human complement and polymorphonuclear leukocytes.

  Capnocytophaga canimorsus is a bacterium of the canine oral flora known since 1976 to cause rare but severe septicemia and peripheral gangrene in pati…

  Authors: Hwain Shin, Manuela Mally, Salome Meyer, Chantal Fiechter, Cécile Paroz, Ulrich Zaehringer, Guy R Cornelis

  Source: Infection and immunity. 2009 Jun

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• A unified model for apical caspase activation.

  Apoptosis is orchestrated by the concerted action of caspases, activated in a minimal two-step proteolytic cascade. Existing data suggests that apical…

  Authors: Kelly M Boatright, Martin Renatus, Fiona L Scott, Sabina Sperandio, Hwain Shin, Irene M Pedersen, Jean Ehrland Ricci, Wade A Edris, Daniel P Sutherlin, Douglas R Green,…

  Source: Molecular cell. 2003 Feb

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• Capnocytophaga canimorsus resists phagocytosis by macrophages and blocks the ability of macrophages to kill other bacteria.

  Capnocytophaga canimorsus is a commensal bacterium from the canine oral flora, which can cause septicemia or meningitis in humans upon bite wound infe…

  Authors: Salome Meyer, Hwain Shin, Guy R Cornelis

  Source: Immunobiology. 2008

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• Capnocytophaga canimorsus: a human pathogen feeding at the surface of epithelial cells and phagocytes.

  Capnocytophaga canimorsus, a commensal bacterium of the canine oral flora, has been repeatedly isolated since 1976 from severe human infections transm…

  Authors: Manuela Mally, Hwain Shin, Cécile Paroz, Regine Landmann, Guy R Cornelis

  Source: PLoS pathogens. 2008

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• Escape from immune surveillance by Capnocytophaga canimorsus.

  Capnocytophaga canimorsus, a commensal bacterium from dogs' mouths, can cause septicemia or meningitis in humans through bites or scratches. Here, we …

  Authors: Hwain Shin, Manuela Mally, Marina Kuhn, Cecile Paroz, Guy R Cornelis

  Source: The Journal of infectious diseases. 2007 Feb 1

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• Caspase 3 attenuates XIAP (X-linked inhibitor of apoptosis protein)-mediated inhibition of caspase 9.

  During apoptosis, the initiator caspase 9 is activated at the apoptosome after which it activates the executioner caspases 3 and 7 by proteolysis. Dur…

  Authors: Jean-Bernard Denault, Brendan P Eckelman, Hwain Shin, Cristina Pop, Guy S Salvesen

  Source: The Biochemical journal. 2007 Jul 1

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• Prevalence of Capnocytophaga canimorsus in dogs and occurrence of potential virulence factors.

  Capnocytophaga canimorsus is a Gram-negative commensal of dog's mouth causing severe human infections. A strain isolated from a human fatal infection …

  Authors: Manuela Mally, Cécile Paroz, Hwain Shin, Salome Meyer, Lavinia V Soussoula, Ueli Schmiediger, Caroline Saillen-Paroz, Guy R Cornelis

  Source: Microbes and infection / Institut Pasteur. 2009 Apr

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• XIAP inhibits caspase-3 and -7 using two binding sites: evolutionarily conserved mechanism of IAPs.

  The X-linked inhibitor of apoptosis protein (XIAP) uses its second baculovirus IAP repeat domain (BIR2) to inhibit the apoptotic executioner caspase-3…

  Authors: Fiona L Scott, Jean-Bernard Denault, Stefan J Riedl, Hwain Shin, Martin Renatus, Guy S Salvesen

  Source: The EMBO journal. 2005 Feb 9

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• The BIR domain of IAP-like protein 2 is conformationally unstable: implications for caspase inhibition.

  Several IAP (inhibitor of apoptosis) proteins regulate cell fate decisions, and the X-linked IAP (XIAP) does so in part by inhibiting caspases, protea…

  Authors: Hwain Shin, Martin Renatus, Brendan P Eckelman, Viviane A Nunes, Claudio A M Sampaio, Guy S Salvesen

  Source: The Biochemical journal. 2005 Jan 1

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