1 to 10 of 47 literature results

• A sensitive and high-throughput assay to detect low-abundance proteins in serum.

  The ability to detect antigens immunologically is limited by the affinity of the antibodies and the amount of antigens. We have now succeeded in creat…

  Authors: Hongtao Zhang, Xin Cheng, Mark Richter, Mark I Greene

  Source: Nature medicine. 2006 Apr

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• A cell-penetrating helical peptide as a potential HIV-1 inhibitor.

  The capsid domain of the human immunodeficiency virus type 1 (HIV-1) Gag polyprotein is a critical determinant of virus assembly, and is therefore a p…

  Authors: Hongtao Zhang, Qian Zhao, Shibani Bhattacharya, Abdul A Waheed, Xiaohe Tong, Anita Hong, Susanne Heck, Francesca Curreli, Michael Goger, David Cowburn,…

  Source: Journal of molecular biology. 2008 May 2

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• UXT is a novel centrosomal protein essential for cell viability.

  Ubiquitously expressed transcript (UXT) is a prefoldinlike protein that has been suggested to be involved in human tumorigenesis. Here, we have found …

  Authors: Huiwu Zhao, Qiang Wang, Hongtao Zhang, Qingdu Liu, Xiulian Du, Mark Richter, Mark I Greene

  Source: Molecular biology of the cell. 2005 Dec

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• The grain size effect on the properties of Aurivillius phase Bi3.15Nd0.85Ti3O12 ferroelectric ceramics.

  Aurivillius phase, bismuth layer structured ferroelectric Bi(3.15)Nd(0.85)Ti(3)O(12) (BNdT) ceramics with average grain sizes from 90 nm and high dens…

  Authors: Hongtao Zhang, Haixue Yan, Huanpo Ning, Michael J Reece, Mirva Eriksson, Zhijian Shen, Yanmei Kan, Peiling Wang

  Source: Nanotechnology. 2009 Sep 23

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• Synthesis and structure-activity relationships of N-substituted spiropiperidines as nociceptin receptor ligands: part 2.

  A series of N-8 substituted analogs based upon the spiropiperidine core of the original lead compound 1 was synthesized. This lead has been elaborated…

  Authors: John P Caldwell, Julius J Matasi, Xiomara Fernandez, Robbie L McLeod, Hongtao Zhang, Ahmad Fawzi, Deen B Tulshian

  Source: Bioorganic & medicinal chemistry letters. 2009 Feb 15

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• Enhancement of vaccine potency by fusing modified LTK63 into human papillomavirus type 16 chimeric virus-like particles.

  To enhance the immunogenicity of human papillomavirus 16 (HPV 16) virus-like particles (VLPs), the modified adjuvant, mLTK63, was fused to the C-termi…

  Authors: Yufei Xu, Hongtao Zhang, Xuemei Xu

  Source: FEMS immunology and medical microbiology. 2008 Jan

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• Induction of mucosal and systemic neutralizing antibodies against human immunodeficiency virus type 1 (HIV-1) by oral immunization with bovine Papillomavirus-HIV-1 gp41 chimeric virus-like particles.

  Human immunodeficiency virus type 1 (HIV-1) envelope-specific neutralizing antibodies are generated late after initial infection, and the neutralizing…

  Authors: Hongtao Zhang, Yujun Huang, Raja Fayad, Gregory T Spear, Liang Qiao

  Source: Journal of virology. 2004 Aug

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• Human immunodeficiency virus type 1 gag-specific mucosal immunity after oral immunization with papillomavirus pseudoviruses encoding gag.

  Mucosal surfaces are the primary portals for human immunodeficiency virus (HIV) transmission. Because systemic immunization, in general, does not indu…

  Authors: Hongtao Zhang, Raja Fayad, Xilin Wang, Daniel Quinn, Liang Qiao

  Source: Journal of virology. 2004 Oct

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• Receptor-targeted cancer therapy.

  Insight into the molecular mechanisms of malignant transformation is changing the way cancer is being treated. Conventional treatment strategies targe…

  Authors: Mark Richter, Hongtao Zhang

  Source: DNA and cell biology. 2005 May

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• Synthesis and structure-activity relationships of N-substituted spiropiperidines as nociceptin receptor ligands.

  A series of N-substituted analogs based upon the spiropiperidine core of 1 was synthesized and exhibited high binding affinity to the nociceptin (NOP)…

  Authors: John P Caldwell, Julius J Matasi, Hongtao Zhang, Ahmad Fawzi, Deen B Tulshian

  Source: Bioorganic & medicinal chemistry letters. 2007 Apr 15

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