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Toward the end of mitosis, neighboring chromosomes gather closely to form a compact cluster. This is important for reassembling the nuclear envelope a…
Authors: Miho Ohsugi, Kenjiro Adachi, Reiko Horai, Shigeru Kakuta, Katsuko Sudo, Hayato Kotaki, Noriko Tokai-Nishizumi, Hiroshi Sagara, Yoichiro Iwakura, Tadashi Yamamoto
Source: Cell. 2008 Mar 7
View Full TextIn viruses, as in eukaryotes, elaborate mechanisms have evolved to protect the genome and to ensure its timely replication and reliable transmission t…
Authors: Takeshi Noda, Hiroshi Sagara, Albert Yen, Ayato Takada, Hiroshi Kida, R Holland Cheng, Yoshihiro Kawaoka
Source: Nature. 2006 Jan 26
View Full TextUs3 is a serine/threonine protein kinase encoded by herpes simplex virus 1 (HSV-1). We recently identified serine at Us3 position 147 (Ser-147) as a p…
Authors: Ken Sagou, Takahiko Imai, Hiroshi Sagara, Masashi Uema, Yasushi Kawaguchi
Source: Journal of virology. 2009 Jun
View Free Full TextBlastocyst formation during mammalian preimplantation development is a unique developmental process that involves lineage segregation between the inne…
Authors: Kenjiro Adachi, Chie Soeta-Saneyoshi, Hiroshi Sagara, Yoichiro Iwakura
Source: Molecular and cellular biology. 2007 Mar
View Free Full TextExpression of Ebola virus nucleoprotein (NP) in mammalian cells leads to the formation of helical structures, which serve as a scaffold for the nucleo…
Authors: Takeshi Noda, Shinji Watanabe, Hiroshi Sagara, Yoshihiro Kawaoka
Source: Journal of virology. 2007 Apr
View Free Full TextNitrogen-containing bisphosphonates are pyrophosphate analogs that have long been the preferred prescription for treating osteoporosis. Although these…
Authors: Yuka Masaike, Takeshi Takagi, Masataka Hirota, Joe Yamada, Satoru Ishihara, Tetsu M C Yung, Takamasa Inoue, Chika Sawa, Hiroshi Sagara, Satoshi Sakamoto,…
Source: Molecular pharmacology. 2010 Feb
View Full TextHerpes simplex virus 1 (HSV-1) enters cells either via fusion of the virion envelope and host cell plasma membrane or via endocytosis, depending on th…
Authors: Jun Arii, Masashi Uema, Tomomi Morimoto, Hiroshi Sagara, Hiroomi Akashi, Etsuro Ono, Hisashi Arase, Yasushi Kawaguchi
Source: Journal of virology. 2009 May
View Free Full TextWe report here the construction of a triply fluorescent-tagged herpes simplex virus 1 (HSV-1) expressing capsid protein VP26, tegument protein VP22, a…
Authors: Ken Sugimoto, Masashi Uema, Hiroshi Sagara, Michiko Tanaka, Tetsutaro Sata, Yasuhiro Hashimoto, Yasushi Kawaguchi
Source: Journal of virology. 2008 Jun
View Free Full TextThe membrane-anchored matrix metalloproteinase MT1-MMP (also known as Mmp14) plays a key role in the angiogenic process, but the mechanisms underlying…
Authors: Ikuo Yana, Hiroshi Sagara, Satoshi Takaki, Kiyoshi Takatsu, Kenji Nakamura, Kazuki Nakao, Motoya Katsuki, Shun-ichiro Taniguchi, Takanori Aoki, Hiroshi Sato,…
Source: Journal of cell science. 2007 May 1
View Full TextProgress is being made toward regenerating teeth by seeding dissociated postnatal odontogenic cells onto scaffolds and implanting them in vivo, but to…
Authors: Masaki J Honda, Shuhei Tsuchiya, Yoshinori Sumita, Hiroshi Sagara, Minoru Ueda
Source: Biomaterials. 2007 Feb
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