1 to 10 of 11 literature results

• The basic leucine zipper transcription factor E4BP4 is essential for natural killer cell development.

  Natural killer (NK) cells are a subset of lymphocytes crucial for innate immunity and modification of adaptive immune responses. In contrast to commit…

  Authors: Duncan M Gascoyne, Elaine Long, Henrique Veiga-Fernandes, Jasper de Boer, Owen Williams, Benedict Seddon, Mark Coles, Dimitris Kioussis, Hugh J M Brady

  Source: Nature immunology. 2009 Oct

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• Tyrosine kinase receptor RET is a key regulator of Peyer's patch organogenesis.

  Normal organogenesis requires co-ordinate development and interaction of multiple cell types, and is seemingly governed by tissue specific factors. Ly…

  Authors: Henrique Veiga-Fernandes, Mark C Coles, Katie E Foster, Amisha Patel, Adam Williams, Dipa Natarajan, Amanda Barlow, Vassilis Pachnis, Dimitris Kioussis

  Source: Nature. 2007 Mar 29

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• High expression of active CDK6 in the cytoplasm of CD8 memory cells favors rapid division.

  Antigen-driven CD8 memory T cell proliferation is more rapid than that of naive T cells, ensuring efficient control of the pathogen after reinfection.…

  Authors: Henrique Veiga-Fernandes, Benedita Rocha

  Source: Nature immunology. 2004 Jan

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• Quantification of multiple gene expression in individual cells.

  Quantitative gene expression analysis aims to define the gene expression patterns determining cell behavior. So far, these assessments can only be per…

  Authors: António Peixoto, Marta Monteiro, Benedita Rocha, Henrique Veiga-Fernandes

  Source: Genome research. 2004 Oct

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• Position effect variegation and imprinting of transgenes in lymphocytes.

  Sequences proximal to transgene integration sites are able to deregulate transgene expression resulting in complex position effect phenotypes. In addi…

  Authors: Adam Williams, Nicola Harker, Eleni Ktistaki, Henrique Veiga-Fernandes, Kathleen Roderick, Mauro Tolaini, Trisha Norton, Keith Williams, Dimitris Kioussis

  Source: Nucleic acids research. 2008 Apr

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• CD8 lethargy in the absence of CD4 help.

  CD4 T cell help was proposed to have a pivotal role in orienting CD8 T cell responses to antigen stimulation. By activating antigen-presenting cells (…

  Authors: Christine Bourgeois, Henrique Veiga-Fernandes, Anne-Marie Joret, Benedita Rocha, Corinne Tanchot

  Source: European journal of immunology. 2002 Aug

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• CD8 single-cell gene coexpression reveals three different effector types present at distinct phases of the immune response.

  To study in vivo CD8 T cell differentiation, we quantified the coexpression of multiple genes in single cells throughout immune responses. After in vi…

  Authors: António Peixoto, César Evaristo, Ivana Munitic, Marta Monteiro, Alain Charbit, Benedita Rocha, Henrique Veiga-Fernandes

  Source: The Journal of experimental medicine. 2007 May 14

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• Contribution of neural crest-derived cells in the embryonic and adult thymus.

  Neural crest (NC)-derived mesenchyme has previously been shown to play an important role in the development of fetal thymus. Using Wnt1-Cre and Sox10-…

  Authors: Katie Foster, Julie Sheridan, Henrique Veiga-Fernandes, Kathleen Roderick, Vassilis Pachnis, Ralf Adams, Clare Blackburn, Dimitris Kioussis, Mark Coles

  Source: Journal of immunology (Baltimore, Md. : 1950). 2008 Mar 1

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• Mll has a critical role in fetal and adult hematopoietic stem cell self-renewal.

  The Mixed Lineage Leukemia (Mll) gene is a homolog of Drosophila Trithorax commonly rearranged in infant leukemia. Comprehensive analysis of the role …

  Authors: Kathryn A McMahon, Samantha Y-L Hiew, Suzana Hadjur, Henrique Veiga-Fernandes, Ursula Menzel, Amanda J Price, Dimitris Kioussis, Owen Williams, Hugh J M Brady

  Source: Cell stem cell. 2007 Sep 13

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• Role of T and NK cells and IL7/IL7r interactions during neonatal maturation of lymph nodes.

  Lymph node (LN) development depends on prenatal interactions occurring between LN inducer and LN organizer cells. We have distinguished defects in LN …

  Authors: Mark C Coles, Henrique Veiga-Fernandes, Katie E Foster, Trisha Norton, Stamatis N Pagakis, Ben Seddon, Dimitris Kioussis

  Source: Proceedings of the National Academy of Sciences of the United States of America. 2006 Sep 5

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