1 to 8 of 8 literature results

• Restrictive left ventricular filling pattern does not result from increased left atrial pressure alone.

  BACKGROUND: The restrictive filling pattern seen with severe heart failure (HF) may be due to diastolic dysfunction with elevated left ventricular (LV…

  Authors: Satoshi Masutani, William C Little, Hiroshi Hasegawa, Heng-Jie Cheng, Che-Ping Cheng

  Source: Circulation. 2008 Mar 25

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• Angiotensin II type 1 receptor blockade prevents alcoholic cardiomyopathy.

  BACKGROUND: Activation of the renin-angiotensin system (RAS) may contribute to the development of alcoholic cardiomyopathy. We evaluated the effect of…

  Authors: Che-Ping Cheng, Heng-Jie Cheng, Carol Cunningham, Zakariya K Shihabi, David C Sane, Thomas Wannenburg, William C Little

  Source: Circulation. 2006 Jul 18

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• Diastolic mitral annular velocity during the development of heart failure.

  OBJECTIVES: We sought to investigate the mechanism of reduced diastolic mitral annular velocity with diastolic dysfunction, despite elevated left atri…

  Authors: Hiroshi Hasegawa, William C Little, Michiya Ohno, Steffen Brucks, Atsushi Morimoto, Heng-Jie Cheng, Che-Ping Cheng

  Source: Journal of the American College of Cardiology. 2003 May 7

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• Pathophysiology of anthrax.

  Infection by Bacillus anthracis in animals and humans results from accidental or intentional exposure, by oral, cutaneous or pulmonary routes, to spor…

  Authors: Arthur E Frankel, Shu-Ru Kuo, David Dostal, Linley Watson, Nicholas S Duesbery, Che-Ping Cheng, Heng Jie Cheng, Stephen H Leppla

  Source: Frontiers in bioscience : a journal and virtual library. 2009

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• Orally available levosimendan dose-related positive inotropic and lusitropic effect in conscious chronically instrumented normal and heart failure dogs.

  Levosimendan (LS), a Ca(2+) sensitizer, is presently limited to i.v. administration. The dose-related pharmacodynamic effects of newly developed oral …

  Authors: Satoshi Masutani, Heng-Jie Cheng, Minja Hyttilä-Hopponen, Jouko Levijoki, Aira Heikkilä, Arja Vuorela, William C Little, Che-Ping Cheng

  Source: The Journal of pharmacology and experimental therapeutics. 2008 Apr

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• Levosimendan improves LV systolic and diastolic performance at rest and during exercise after heart failure.

  The new myofilament Ca2+ sensitizer levosimendan (LSM) is a positive inotropic and vasodilatory agent. Its beneficial effects have been demonstrated a…

  Authors: Hideo Tachibana, Heng-Jie Cheng, Tomohiko Ukai, Akihiko Igawa, Zhu-Shan Zhang, William C Little, Che-Ping Cheng

  Source: American journal of physiology. Heart and circulatory physiology. 2005 Feb

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• Endogenous beta3-adrenoreceptor activation contributes to left ventricular and cardiomyocyte dysfunction in heart failure.

  The objective of the present study was to test the hypothesis that endogenous beta(3)-adrenoreceptor (AR) activation contributes to left ventricular (…

  Authors: Atsushi Morimoto, Hiroshi Hasegawa, Heng-Jie Cheng, William C Little, Che-Ping Cheng

  Source: American journal of physiology. Heart and circulatory physiology. 2004 Jun

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• Enhanced inhibition of L-type Ca2+ current by beta3-adrenergic stimulation in failing rat heart.

  beta3-adrenergic receptors (AR) have recently been identified in mammalian hearts and shown to be up-regulated in heart failure (HF). beta3-AR stimula…

  Authors: Zhu-Shan Zhang, Heng-Jie Cheng, Katsuya Onishi, Nobuyuki Ohte, Thomas Wannenburg, Che-Ping Cheng

  Source: The Journal of pharmacology and experimental therapeutics. 2005 Dec

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