1 to 10 of 102 literature results

• Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions.

  Frontotemporal lobar degeneration (FTLD) is the second most common cause of presenile dementia. The predominant neuropathology is FTLD with TAR DNA-bi…

  Authors: Vivianna M Van Deerlin, Patrick M A Sleiman, Maria Martinez-Lage, Alice Chen-Plotkin, Li-San Wang, Neill R Graff-Radford, Dennis W Dickson, Rosa Rademakers, Bradley F Boeve, Murray Grossman,…

  Source: Nature genetics. 2010 Mar

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• Pathologic findings in retinal pigment epithelial cell implantation for Parkinson disease.

  BACKGROUND: Attempts at cell-based dopamine replacement therapy in Parkinson disease (PD) have included surgical implantation of adrenal medullary, fe…

  Authors: Emad S Farag, Harry V Vinters, Jeff Bronstein

  Source: Neurology. 2009 Oct 6

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• Astrocytes: biology and pathology.

  Astrocytes are specialized glial cells that outnumber neurons by over fivefold. They contiguously tile the entire central nervous system (CNS) and exe…

  Authors: Michael V Sofroniew, Harry V Vinters

  Source: Acta neuropathologica. 2010 Jan

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• Genome wide profiling of altered gene expression in the neocortex of Alzheimer's disease.

  Alzheimer's disease (AD) is characterized by a complex neurodegenerative process affecting multiple genes and proteins in the neocortex, many of which…

  Authors: Michelle G Tan, Wei-Ting Chua, Margaret M Esiri, A David Smith, Harry V Vinters, Mitchell K Lai

  Source: Journal of neuroscience research. 2010 May 1

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• Increased activation of Iba1+ microglia in pediatric epilepsy patients with Rasmussen's encephalitis compared with cortical dysplasia and tuberous sclerosis complex.

  Microgliosis is prominent in Rasmussen's encephalitis (RE), a disease with severe seizure activity. However, it is unclear if microglial activation is…

  Authors: Martin Wirenfeldt, Ryan Clare, Spencer Tung, Alexander Bottini, Gary W Mathern, Harry V Vinters

  Source: Neurobiology of disease. 2009 Jun

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• Effects of anoxia and hypoxia on amyloid precursor protein processing in cerebral microvascular smooth muscle cells.

  Cerebral amyloid angiopathy (CAA) is characterized by the degeneration of cerebral microvascular smooth muscle cells (MV-SMC) and the replacement of n…

  Authors: Ilene D Auerbach, Harry V Vinters

  Source: Journal of neuropathology and experimental neurology. 2006 Jun

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• Imaging cerebral microvascular amyloid.

  Authors: Harry V Vinters

  Source: Annals of neurology. 2007 Sep

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• Insulin signaling pathways in cortical dysplasia and TSC-tubers: tissue microarray analysis.

  To evaluate the possible roles of the Akt/PKB-mTOR-p70S6K-S6 and cap-dependent translation (eIF4G) pathways in the pathogenesis of tuberous sclerosis …

  Authors: Hajime Miyata, Alexander C Y Chiang, Harry V Vinters

  Source: Annals of neurology. 2004 Oct

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• Alterations in NMDA receptor subunit densities and ligand binding to glycine recognition sites are associated with chronic anxiety in Alzheimer's disease.

  Glutamatergic deficits are established neuropathological features of Alzheimer's disease (AD) and are known to correlate with cognitive impairments. I…

  Authors: Shirley W Y Tsang, Harry V Vinters, Jeffrey L Cummings, Peter T-H Wong, Christopher P L-H Chen, Mitchell K P Lai

  Source: Neurobiology of aging. 2008 Oct

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• A genomic screen for modifiers of tauopathy identifies puromycin-sensitive aminopeptidase as an inhibitor of tau-induced neurodegeneration.

  Neurofibrillary tangles (NFT) containing tau are a hallmark of neurodegenerative diseases, including Alzheimer's disease (AD). NFT burden correlates w…

  Authors: Stanislav L Karsten, Tzu-Kang Sang, Lauren T Gehman, Shreyasi Chatterjee, Jiankai Liu, George M Lawless, Soma Sengupta, Robert W Berry, Justine Pomakian, Hyun S Oh,…

  Source: Neuron. 2006 Sep 7

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