1 to 10 of 262 literature results

• Macrophage receptors and immune recognition.

  Macrophages express a broad range of plasma membrane receptors that mediate their interactions with natural and altered-self components of the host as…

  Authors: P R Taylor, L Martinez-Pomares, M Stacey, H-H Lin, G D Brown, S Gordon

  Source: Annual review of immunology. 2005

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• Human p16gamma, a novel transcriptional variant of p16(INK4A), coexpresses with p16(INK4A) in cancer cells and inhibits cell-cycle progression.

  The INK4A locus encodes two tumor suppressor genes, p16(INK4A) and p14(ARF), transcribed using alternative exons 1alpha or 1beta spliced onto the same…

  Authors: Y-C Lin, M B Diccianni, Y Kim, H-H Lin, C-H Lee, R-J Lin, S H Joo, J Li, T-J Chuang, A-S Yang,…

  Source: Oncogene. 2007 Oct 25

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• Involvement of protein kinase C and Src tyrosine kinase in acute tolerance to ethanol inhibition of spinal NMDA-induced pressor responses in rats.

  BACKGROUND AND PURPOSE: The present study was carried out to examine the role of protein kinases in the development of acute tolerance to the effects …

  Authors: W-K Hsieh, H-H Lin, C-C Lai

  Source: British journal of pharmacology. 2009 Oct

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• PROFEAT: a web server for computing structural and physicochemical features of proteins and peptides from amino acid sequence.

  Sequence-derived structural and physicochemical features have frequently been used in the development of statistical learning models for predicting pr…

  Authors: Z R Li, H H Lin, L Y Han, L Jiang, X Chen, Y Z Chen

  Source: Nucleic acids research. 2006 Jul 1

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• Prediction of the functional class of lipid binding proteins from sequence-derived properties irrespective of sequence similarity.

  Lipid binding proteins play important roles in signaling, regulation, membrane trafficking, immune response, lipid metabolism, and transport. Because …

  Authors: H H Lin, L Y Han, H L Zhang, C J Zheng, B Xie, Y Z Chen

  Source: Journal of lipid research. 2006 Apr

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• LNB-TM7, a group of seven-transmembrane proteins related to family-B G-protein-coupled receptors.

  A number of unusual seven-transmembrane molecules have recently been characterized that have significant amino acid sequence similarity within the mem…

  Authors: M Stacey, H H Lin, S Gordon, A J McKnight

  Source: Trends in biochemical sciences. 2000 Jun

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• Intravenous iron attenuates postvaccination anti-HBsAg titres after quadruple hepatitis B vaccination in dialysis patients with erythropoietin therapy.

  BACKGROUND: Anaemia in patients with end-stage renal disease (ESRD) is commonly treated with recombinant human erythropoietin (rHuEPO), often in combi…

  Authors: J-H Liu, Y-L Liu, H-H Lin, Y-F Yang, H-L Kuo, P-W Lin, C-C Huang

  Source: International journal of clinical practice. 2009 Mar

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• A support vector machines approach for virtual screening of active compounds of single and multiple mechanisms from large libraries at an improved hit-rate and enrichment factor.

  Support vector machines (SVM) and other machine-learning (ML) methods have been explored as ligand-based virtual screening (VS) tools for facilitating…

  Authors: L Y Han, X H Ma, H H Lin, J Jia, F Zhu, Y Xue, Z R Li, Z W Cao, Z L Ji, Y Z Chen

  Source: Journal of molecular graphics & modelling. 2008 Jun

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• MoViES: molecular vibrations evaluation server for analysis of fluctuational dynamics of proteins and nucleic acids.

  Analysis of vibrational motions and thermal fluctuational dynamics is a widely used approach for studying structural, dynamic and functional propertie…

  Authors: Z W Cao, Y Xue, L Y Han, B Xie, H Zhou, C J Zheng, H H Lin, Y Z Chen

  Source: Nucleic acids research. 2004 Jul 1

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• Prediction of factor Xa inhibitors by machine learning methods.

  Factor Xa (FXa) inhibitors have been explored as anticoagulants for treatment and prevention of thrombotic diseases. Molecular docking, pharmacophore,…

  Authors: H H Lin, L Y Han, C W Yap, Y Xue, X H Liu, F Zhu, Y Z Chen

  Source: Journal of molecular graphics & modelling. 2007 Sep

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