9 literature results

• Introduction of moribund category to OECD fish acute test and its effect on suffering and LC50 values.

  It has become common practice in many laboratories in Europe to introduce the criterion "moribund" to reduce the suffering in fish acute lethality tes…

  Authors: Hans Rufli

  Source: Environmental toxicology and chemistry / SETAC. 2012 Feb 23

  View Full Text

• Can we reduce the number of fish in the OECD acute toxicity test?

  OECD (Organisation for Economic Co-operation and Development) Guideline 203, Fish Acute Toxicity Test, states that the test should be performed using …

  Authors: Hans Rufli, Timothy A Springer

  Source: Environmental toxicology and chemistry / SETAC. 2011 Apr

  View Full Text

• The chironomid acute toxicity test: development of a new test system.

  This paper describes the basis for a water-only acute chironomid toxicity test guideline using first-instar larvae. The method is based on the OECD te…

  Authors: Lennart Weltje, Hans Rufli, Fred Heimbach, James Wheeler, Marco Vervliet-Scheebaum, Michael Hamer

  Source: Integrated environmental assessment and management. 2010 Apr

  View Full Text

• Environmental effect assessment for sexual endocrine-disrupting chemicals: Fish testing strategy.

  Current standard testing and assessment tools are not designed to identify specific and biologically highly sensitive modes of action of chemicals, su…

  Authors: Thomas Knacker, Melanie Boettcher, Tobias Frische, Hans Rufli, Hans-Christian Stolzenberg, Matthias Teigeler, Sabine Zok, Thomas Braunbeck, Christoph Schäfers

  Source: Integrated environmental assessment and management. 2010 Oct

  View Full Text

• Determination of vitellogenin kinetics in male fathead minnows (Pimephales promelas).

  A lack of knowledge persists concerning the combination of kinetics on protein and mRNA levels of the most commonly used biomarker for estrogenic infl…

  Authors: T Schmid, J Gonzalez-Valero, H Rufli, D R Dietrich

  Source: Toxicology letters. 2002 May 10

  View Full Text

• Multi-criteria decision analysis of test endpoints for detecting the effects of endocrine active substances in fish full life cycle tests.

  Fish full life cycle (FFLC) tests are increasingly required in the ecotoxicological assessment of endocrine active substances. However, FFLC tests hav…

  Authors: Mark Crane, Melanie Gross, Peter Matthiessen, Gerald T Ankley, Stephen Axford, Poul Bjerregaard, Ross Brown, Peter Chapman, Michael Dorgeloh, Malyka Galay-Burgos,…

  Source: Integrated environmental assessment and management. 2010 Jul

  View Full Text

• The use of fish cells in ecotoxicology. The report and recommendations of ECVAM Workshop 47.

  Authors: Argelia Castaño, Niels Bols, Thomas Braunbeck, Paul Dierickx, Marlies Halder, Boris Isomaa, Kazumi Kawahara, Lucy E J Lee, Carmel Mothersill, Peter Pärt,…

  Source: Alternatives to laboratory animals : ATLA. 2003 May-Jun

  View Full Text

• Aquatic toxicity testing of sparingly soluble, volatile, and unstable substances and interpretation and use of data. Task Force of the European Centre for Ecotoxicology and Toxicology of Chemicals.

  Aquatic toxicity tests were originally designed for individual compounds that are soluble and stable in water. For sparingly soluble substances that a…

  Authors: H Rufli, P R Fisk, A E Girling, J M King, R Länge, X Lejeune, N Stelter, C Stevens, P Suteau, J Tapp,…

  Source: Ecotoxicology and environmental safety. 1998 Feb

  View Full Text

• Treatment of therapy-resistant leg ulcer using repeated applications of foreign skin (homologous transplants)].

  Authors: S Krupp, T h Rufli

  Source: Schweizerische medizinische Wochenschrift. 1974 Aug 17

  View Full Text