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Activation of G protein-coupled receptors: beyond two-state models and tertiary conformational changes.
Transformation of G protein-coupled receptors (GPCRs) from a quiescent to an active state initiates signal transduction. All GPCRs share a common arch…
Authors: Paul S-H Park, David T Lodowski, Krzysztof Palczewski
Source: Annual review of pharmacology and toxicology. 2008
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Generation of single optical plasmons in metallic nanowires coupled to quantum dots.
Control over the interaction between single photons and individual optical emitters is an outstanding problem in quantum science and engineering. It i…
Authors: A V Akimov, A Mukherjee, C L Yu, D E Chang, A S Zibrov, P R Hemmer, H Park, M D Lukin
Source: Nature. 2007 Nov 15
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A highly annotated whole-genome sequence of a Korean individual.
Recent advances in sequencing technologies have initiated an era of personal genome sequences. To date, human genome sequences have been reported for …
Authors: Jong-Il Kim, Young Seok Ju, Hansoo Park, Sheehyun Kim, Seonwook Lee, Jae-Hyuk Yi, Joann Mudge, Neil A Miller, Dongwan Hong, Callum J Bell,…
Source: Nature. 2009 Aug 20
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Cdc42 regulates Fc gamma receptor-mediated phagocytosis through the activation and phosphorylation of Wiskott-Aldrich syndrome protein (WASP) and neural-WASP.
Cdc42 is a key regulator of the actin cytoskeleton and activator of Wiskott-Aldrich syndrome protein (WASP). Although several studies have separately …
Authors: Haein Park, Dianne Cox
Source: Molecular biology of the cell. 2009 Nov
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X-linked inhibitor of apoptosis protein is an important regulator of vascular endothelial growth factor-dependent bovine aortic endothelial cell survival.
Vascular endothelial growth factor (VEGF) is a critical regulator of endothelial cell biology and vascular function. Chronic VEGF treatment has been s…
Authors: Jongmin Kim, Jongbong Park, Seungmin Choi, Sung-Gil Chi, Amy L Mowbray, Hanjoong Jo, Heonyong Park
Source: Circulation research. 2008 Apr 25
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Rich variety of defects in ZnO via an attractive interaction between O vacancies and Zn interstitials: origin of n-type doping.
As the concentration of intrinsic defects becomes sufficiently high in O-deficient ZnO, interactions between defects lead to a significant reduction i…
Authors: Yong-Sung Kim, C H Park
Source: Physical review letters. 2009 Feb 27
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Nuclear translocation of CAM-associated protein activates transcription for long-term facilitation in Aplysia.
Repeated pulses of serotonin (5-HT) induce long-term facilitation (LTF) of the synapses between sensory and motor neurons of the gill-withdrawal refle…
Authors: Seung-Hee Lee, Chae-Seok Lim, Hyungju Park, Jin-A Lee, Jin-Hee Han, Hyoung Kim, Ye-Hwang Cheang, Sue-Hyun Lee, Yong-Seok Lee, Hyoung-Gon Ko,…
Source: Cell. 2007 May 18
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Single-molecule fluorescence to study molecular motors.
Molecular motors, which use energy from ATP hydrolysis to take nanometer-scale steps with run-lengths on the order of micrometers, have important role…
Authors: Hyokeun Park, Erdal Toprak, Paul R Selvin
Source: Quarterly reviews of biophysics. 2007 Feb
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Memory systems do not divide on consciousness: Reinterpreting memory in terms of activation and binding.
There is a popular hypothesis that performance on implicit and explicit memory tasks reflects 2 distinct memory systems. Explicit memory is said to st…
Authors: Lynne M Reder, Heekyeong Park, Paul D Kieffaber
Source: Psychological bulletin. 2009 Jan
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Cluster dynamical mean field theory of the Mott transition.
We address the nature of the Mott transition in the Hubbard model at half-filling using cluster dynamical mean field theory (DMFT). We compare cluster…
Authors: H Park, K Haule, G Kotliar
Source: Physical review letters. 2008 Oct 31
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