1 to 10 of 27 literature results

• Dose escalation with repeated intrathecal injections of 131I-labelled MAbs for the treatment of central nervous system malignancies.

  We have previously demonstrated a 33% response rate in patients with primitive neurectodermal tumours after the direct injection of 131I-monoclonal an…

  Authors: J T Kemshead, K Hopkins, B Pizer, V Papanastassiou, H Coakham, J Bullimore, C Chandler

  Source: British journal of cancer. 1998 Jun

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• A mutation in the neurofibromatosis type 2 tumor-suppressor gene, giving rise to widely different clinical phenotypes in two unrelated individuals.

  We have sought mutations in the recently identified neurofibromatosis type 2 (NF2) tumor-suppressor gene in a large panel of NF2 patients, using PCR-b…

  Authors: D Bourn, S A Carter, D G Evans, J Goodship, H Coakham, T Strachan

  Source: American journal of human genetics. 1994 Jul

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• Central nervous system metastasis in Wilms' tumor: a review of three consecutive United Kingdom trials.

  BACKGROUND: Central nervous system (CNS) metastasis is an uncommon event in pediatric oncology, and typically occurs at the end stage of the disease. …

  Authors: S P Lowis, A Foot, M P Gerrard, A Charles, J Imeson, H Middleton, H Coakham, E Bouffet

  Source: Cancer. 1998 Nov 1

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• Surface antigen(s) common to human astrocytoma cells.

  Authors: H Coakham

  Source: Nature. 1974 Jul 26

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• Neuronal hamartoma of the trigeminal sensory root associated with trigeminal neuralgia.

  Authors: N Patel, T Moss, H Coakham

  Source: Journal of neurosurgery. 2000 Sep

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• Miniaturised ultrasonic aspiration handpiece for increased applicability.

  OBJECTIVE: At present, ultrasonic aspiration is routinely used in several fields of surgery, especially in brain and spinal micro-surgery for tumour r…

  Authors: H Wiksell, H Martin, H Coakham, A Berggren, S Westermark

  Source: European journal of ultrasound : official journal of the European Federation of Societies for Ultrasound in Medicine and Biology. 2000 Mar

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• Expression of LFA-1/ICAM-1 in CNS lymphomas: possible mechanism for lymphoma homing into the brain.

  We examined a possible role for the adhesion molecules LFA-1 and ICAM-1 in localizing central nervous system non-Hodgkin's lymphomas (CNS-NHLs) to the…

  Authors: R Bashir, H Coakham, F Hochberg

  Source: Journal of neuro-oncology. 1992 Feb

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• A pilot study of monoclonal antibody targeted radiotherapy in the treatment of central nervous system leukaemia in children.

  A pilot study was performed to investigate the toxicity, pharmacokinetics and therapeutic effect of intrathecally administered radiolabelled monoclona…

  Authors: B Pizer, V Papanastassiou, J Hancock, W Cassano, H Coakham, J Kemshead

  Source: British journal of haematology. 1991 Apr

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• Middle cranial fossa arachnoid cysts: not always a benign entity.

  Arachnoid cysts are often discovered as incidental findings on cranial imaging. A rare manifestation is described in a child presenting acutely with s…

  Authors: M P Callaway, S A Renowden, T T Lewis, J Bradshaw, G Malcolm, H Coakham

  Source: The British journal of radiology. 1998 Apr

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• Chemotherapy for spinal cord astrocytoma: can natural history be modified?

  Standard treatment of spinal cord astrocytomas is based upon surgery, followed by radiotherapy when resection is incomplete or when histology is of hi…

  Authors: S P Lowis, B L Pizer, H Coakham, R J Nelson, E Bouffet

  Source: Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery. 1998 Jul

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