1 to 10 of 59 literature results

• CSF-1R, DAP12 and beta-catenin: a ménage à trois.

  DAP12-coupled receptors influence signals emanating from Toll-like receptors, integrins and receptors for cytokines and growth factors. New findings i…

  Authors: Daniel W McVicar, Giorgio Trinchieri

  Source: Nature immunology. 2009 Jul

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• Reinforcing suppression using regulators: a new link between STAT3, IL-23, and Tregs in tumor immunosuppression.

  STAT3 plays many roles in tumorigenesis. In this issue of Cancer Cell, Kortylewski et al. show that in the tumor microenvironment, STAT3 enhances the …

  Authors: C Andrew Stewart, Giorgio Trinchieri

  Source: Cancer cell. 2009 Feb 3

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• Plasmacytoid dendritic cells in immunity.

  Human and mouse plasmacytoid dendritic cells have been shown to correspond to a specialized cell population that produces large amounts of type I inte…

  Authors: Marco Colonna, Giorgio Trinchieri, Yong-Jun Liu

  Source: Nature immunology. 2004 Dec

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• IL-10 or not IL-10: that is the question.

  Authors: Dragana Jankovic, Giorgio Trinchieri

  Source: Nature immunology. 2007 Dec

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• Plasmacytoid dendritic cells mediate oral tolerance.

  Oral tolerance prevents oral sensitization to dietary antigens (Ags), including proteins and haptens, and development of delayed-type hypersensitivity…

  Authors: Anne Goubier, Bertrand Dubois, Hanane Gheit, Grégoire Joubert, Florence Villard-Truc, Carine Asselin-Paturel, Giorgio Trinchieri, Dominique Kaiserlian

  Source: Immunity. 2008 Sep 19

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• Alloantigen-presenting plasmacytoid dendritic cells mediate tolerance to vascularized grafts.

  The induction of alloantigen-specific unresponsiveness remains an elusive goal in organ transplantation. Here we identify plasmacytoid dendritic cells…

  Authors: Jordi C Ochando, Chiho Homma, Yu Yang, Andres Hidalgo, Alexandre Garin, Frank Tacke, Veronique Angeli, Yansui Li, Peter Boros, Yaozhong Ding,…

  Source: Nature immunology. 2006 Jun

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• Interaction between conventional dendritic cells and natural killer cells is integral to the activation of effective antiviral immunity.

  Dendritic cells (DCs) regulate various aspects of innate immunity, including natural killer (NK) cell function. Here we define the mechanisms involved…

  Authors: Christopher E Andoniou, Serani L H van Dommelen, Valentina Voigt, Daniel M Andrews, Geraldine Brizard, Carine Asselin-Paturel, Thomas Delale, Katryn J Stacey, Giorgio Trinchieri, Mariapia A Degli-Esposti

  Source: Nature immunology. 2005 Oct

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• Regulation of interleukin-12/interleukin-23 production and the T-helper 17 response in humans.

  Interleukin-12 (IL-12) and IL-23 share a common chain. Yet, their production in response to pathogens is differentially regulated, and their functions…

  Authors: Lyudmila Lyakh, Giorgio Trinchieri, Lisa Provezza, Giuseppe Carra, Franca Gerosa

  Source: Immunological reviews. 2008 Dec

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• Innate resistance and inflammation.

  Authors: Siamon Gordon, Giorgio Trinchieri

  Source: Current opinion in immunology. 2009 Feb

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• The IL-12 family of heterodimeric cytokines: new players in the regulation of T cell responses.

  Originally the only known heterodimeric cytokine, IL-12 is now part of a family of five cytokines and shares important functions in the regulation of …

  Authors: Giorgio Trinchieri, Stefan Pflanz, Robert A Kastelein

  Source: Immunity. 2003 Nov

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