1 to 10 of 18 literature results

• Silencing DJ-1 reveals its contribution in paraquat-induced autophagy.

  The role of autophagy as a survival strategy of cells constitutes an emerging topic in the study of the pathogenesis of several diseases with autophag…

  Authors: Rosa González-Polo, Mireia Niso-Santano, José M Morán, Miguel A Ortiz-Ortiz, José M Bravo-San Pedro, Germán Soler, José M Fuentes

  Source: Journal of neurochemistry. 2009 May

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• Arginase I is constitutively expressed in human granulocytes and participates in fungicidal activity.

  The balance of arginine metabolism via nitric oxide synthase (NOS) or arginase is an important determinant of the inflammatory response of murine macr…

  Authors: Markus Munder, Faustino Mollinedo, Jero Calafat, Javier Canchado, Cristina Gil-Lamaignere, José M Fuentes, Claudia Luckner, Gwendolyn Doschko, Germán Soler, Klaus Eichmann,…

  Source: Blood. 2005 Mar 15

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• MPP+: mechanism for its toxicity in cerebellar granule cells.

  Cerebellar granule cells constitute the largest homogeneous neuronal population of the mammalian brain. However, they are not often used in studies th…

  Authors: Rosa A González-Polo, Germán Soler, José M Fuentes

  Source: Molecular neurobiology. 2004 Dec

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• Curcumin enhances paraquat-induced apoptosis of N27 mesencephalic cells via the generation of reactive oxygen species.

  Curcumin, the active compound of the rhizome of Curcuma longa has anti-inflammatory, antioxidant and antiproliferative activities. This agent has been…

  Authors: Miguel A Ortiz-Ortiz, José M Morán, Jose M Bravosanpedro, Rosa A González-Polo, Mireia Niso-Santano, Vellareddy Anantharam, Anumantha G Kanthasamy, Germán Soler, José M Fuentes

  Source: Neurotoxicology. 2009 Nov

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• Arginase activity mediates reversible T cell hyporesponsiveness in human pregnancy.

  Complex regulation of T cell functions during pregnancy is required to ensure materno-fetal tolerance. Here we reveal a novel pathway for the temporar…

  Authors: Pascale Kropf, David Baud, Sara E Marshall, Markus Munder, Angelina Mosley, José M Fuentes, Charles R M Bangham, Graham P Taylor, Shanti Herath, Beak-San Choi,…

  Source: European journal of immunology. 2007 Apr

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• Vitamin E blocks early events induced by 1-methyl-4-phenylpyridinium (MPP+) in cerebellar granule cells.

  Exposure of cerebellar granule cells (CGCs) to 1-methyl-4-phenylpyridinium (MPP+) results in apoptotic cell death, which is markedly attenuated by co-…

  Authors: Rosa A González-Polo, Germán Soler, Alberto Alvarez, Isabel Fabregat, José M Fuentes

  Source: Journal of neurochemistry. 2003 Jan

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• Lithium blocks the PKB and GSK3 dephosphorylation induced by ceramide through protein phosphatase-2A.

  The biochemical mechanism of apoptosis induced by ceramide remains still unclear, although it has been reported that dephosphorylation of PKB at Ser-4…

  Authors: Alfonso Mora, Guadalupe Sabio, Ana María Risco, Ana Cuenda, Juan C Alonso, Germán Soler, Francisco Centeno

  Source: Cellular signalling. 2002 Jun

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• Different dependence of lithium and valproate on PI3K/PKB pathway.

  OBJECTIVES: Acute treatment with valproate (VPA) or lithium (Li+) protects cerebellar granule cells (CGC) against apoptosis induced by low potassium (…

  Authors: Alfonso Mora, Guadalupe Sabio, Juan C Alonso, Germán Soler, Francisco Centeno

  Source: Bipolar disorders. 2002 Jun

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• Heat shock proteins protect both MPP(+) and paraquat neurotoxicity.

  The exposure of immortalized rat neuroblast cells to MPP(+) and paraquat results in cell death. Heat shock pre-treatment prior to the addition of MPP(…

  Authors: Vanessa Donaire, Mireia Niso, Jose M Morán, Lourdes García, Rosa A González-Polo, Germán Soler, José M Fuentes

  Source: Brain research bulletin. 2005 Nov 30

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• Paraquat-induced apoptotic cell death in cerebellar granule cells.

  We examined the toxicity of paraquat, a possible environmental risk factor for neurodegenerative disorders like Parkinson's disease (PD). Paraquat is …

  Authors: Rosa A González-Polo, Andrea Rodríguez-Martín, José M Morán, Mireia Niso, Germán Soler, José M Fuentes

  Source: Brain research. 2004 Jun 18

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