1 to 10 of 31 literature results

• Effect of glucosamine sulfate on hip osteoarthritis: a randomized trial.

  BACKGROUND: The effectiveness of glucosamine sulfate as a symptom and disease modifier for osteoarthritis is still under debate. OBJECTIVE: To assess …

  Authors: Rianne M Rozendaal, Bart W Koes, Gerjo J V M van Osch, Elian J Uitterlinden, Eric H Garling, Sten P Willemsen, Abida Z Ginai, Jan A N Verhaar, Harrie Weinans, Sita M A Bierma-Zeinstra

  Source: Annals of internal medicine. 2008 Feb 19

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• Cartilage repair: past and future--lessons for regenerative medicine.

  Since the first cell therapeutic study to repair articular cartilage defects in the knee in 1994, several clinical studies have been reported. An over…

  Authors: Gerjo J V M van Osch, Mats Brittberg, James E Dennis, Yvonne M Bastiaansen-Jenniskens, Reinhold G Erben, Yrjö T Konttinen, Frank P Luyten

  Source: Journal of cellular and molecular medicine. 2009 May

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• Identification of acid-sensing ion channels in bone.

  Bone balances serum pH variations and both osteoclasts and osteoblasts are regulated by subtle changes in pH. The aim of the current study was to iden…

  Authors: Holger Jahr, Marjolein van Driel, Gerjo J V M van Osch, Harrie Weinans, Johannes P T M van Leeuwen

  Source: Biochemical and biophysical research communications. 2005 Nov 11

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• Improved cartilage integration and interfacial strength after enzymatic treatment in a cartilage transplantation model.

  The objective of the present study was to investigate whether treatment of articular cartilage with hyaluronidase and collagenase enhances histologica…

  Authors: Jarno van de Breevaart Bravenboer, Caroline D In der Maur, P Koen Bos, Louw Feenstra, Jan A N Verhaar, Harrie Weinans, Gerjo J V M van Osch

  Source: Arthritis research & therapy. 2004

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• Fibroblasts accelerate culturing of mucosal substitutes.

  Reconstruction of large mucosal defects of the floor of the mouth is typically performed with keratinizing skin. Drawbacks include donor site defects …

  Authors: Hinne A Rakhorst, Sandra J Posthumus-Van Sluijs, Wendy M W Tra, Johan W Van Neck, Gerjo J V M Van Osch, Steven E R Hovius, Abdoelwaheb El Ghalbzouri, Stefan O P Hofer

  Source: Tissue engineering. 2006 Aug

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• Multiplication of human chondrocytes with low seeding densities accelerates cell yield without losing redifferentiation capacity.

  To treat a cartilage defect with tissue-engineering techniques, multiplication of donor cells is essential. However, during this multiplication in mon…

  Authors: Erik W Mandl, Simone W van der Veen, Jan A N Verhaar, Gerjo J V M van Osch

  Source: Tissue engineering. 2004 Jan-Feb

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• Serum-free medium supplemented with high-concentration FGF2 for cell expansion culture of human ear chondrocytes promotes redifferentiation capacity.

  For tissue engineering of autologous cartilage, cell expansion is needed to obtain the cell numbers required. Standard expansion media contain bovine …

  Authors: Erik W Mandl, Simone W van der Veen, Jan A N Verhaar, Gerjo J V M van Osch

  Source: Tissue engineering. 2002 Aug

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• Localization of the potential zonal marker clusterin in native cartilage and in tissue-engineered constructs.

  An increasing number of studies aim to engineer cartilage tissue that more closely mimic the zonal organization of native articular tissue. Further un…

  Authors: Jos Malda, Werner ten Hoope, Wouter Schuurman, Gerjo J V M van Osch, Paul René van Weeren, Wouter J A Dhert

  Source: Tissue engineering. Part A. 2010 Mar

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• Calcineurin inhibitors promote chondrogenic marker expression of dedifferentiated human adult chondrocytes via stimulation of endogenous TGFbeta1 production.

  In vitro chondrocyte expansion is required for several cell-based approaches for the repair of chondral lesions. During expansion, loss of chondrogeni…

  Authors: Anna E van der Windt, Holger Jahr, Eric Farrell, Jan A N Verhaar, Harrie Weinans, Gerjo J V M van Osch

  Source: Tissue engineering. Part A. 2010 Jan

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• Adult human bone marrow- and adipose tissue-derived stromal cells support the formation of prevascular-like structures from endothelial cells in vitro.

  Inadequate vascularization of in vitro-engineered tissue constructs after implantation is a major problem in most tissue-engineering applications. In …

  Authors: Femke Verseijden, Sandra J Posthumus-van Sluijs, Predrag Pavljasevic, Stefan O P Hofer, Gerjo J V M van Osch, Eric Farrell

  Source: Tissue engineering. Part A. 2010 Jan

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