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K(+) channels are widely distributed in both plant and animal cells where they serve many distinct functions. K(+) channels set the membrane potential…
Authors: Steven C Hebert, Gary Desir, Gerhard Giebisch, Wenhui Wang
Source: Physiological reviews. 2005 Jan
View Full TextStimulation of the basolateral Na(+)/K(+)-ATPase in the isolated perfused rabbit cortical collecting duct by raising either bath potassium or lumen so…
Authors: Shigeaki Muto, Shuichi Tsuruoka, Yukio Miyata, Akio Fujimura, Eiji Kusano, Wenhui Wang, Donald Seldin, Gerhard Giebisch
Source: Kidney international. 2009 Jan
View Full TextA key question in systems biology is how diverse physiologic processes are integrated to produce global homeostasis. Genetic analysis can contribute b…
Authors: Kristopher T Kahle, Frederick H Wilson, Qiang Leng, Maria D Lalioti, Anthony D O'Connell, Ke Dong, Alicia K Rapson, Gordon G MacGregor, Gerhard Giebisch, Steven C Hebert,…
Source: Nature genetics. 2003 Dec
View Full TextHomer Smith was, for three decades, from the 1930s until his death in 1962, one of the leaders in the field of renal physiology. His contributions wer…
Authors: Gerhard Giebisch
Source: Journal of nephrology. 2004 Jan-Feb
View Full TextA complex pump-leak system involving both active and passive transport mechanisms is responsible for the appropriate distribution of potassium (K) bet…
Authors: Gerhard Giebisch
Source: Wiener klinische Wochenschrift. 2004 Jun 30
View Full TextAuthors: Gerhard Giebisch
Source: Kidney international. 2003 Jun
View Full TextThis review provides an overview of the molecular mechanisms of K transport in the mammalian connecting tubule (CNT) and cortical collecting duct (CCD…
Authors: Wen-Hui Wang, Gerhard Giebisch
Source: Pflügers Archiv : European journal of physiology. 2009 May
View Free Full TextWNK4 (with no lysine kinase 4) inhibits ROMK channel activity in the distal nephron by stimulating clathrin-dependent endocytosis, an effect attenuate…
Authors: Peng Yue, Dao-Hong Lin, Chun-Yang Pan, Qiang Leng, Gerhard Giebisch, Richard P Lifton, Wen-Hui Wang
Source: Proceedings of the National Academy of Sciences of the United States of America. 2009 Sep 1
View Free Full TextThis essay looks at the historical significance of two APS classic papers that are freely available online: Pitts RF and Alexander RS. The nature of t…
Authors: Gerhard Giebisch
Source: American journal of physiology. Renal physiology. 2004 Nov
View Full TextROMK null mice with a high survival rate and varying severity of hydronephrosis provide a good model to study type II Bartter syndrome pathophysiology…
Authors: Qingshang Yan, Xinbo Yang, Alessandra Cantone, Gerhard Giebisch, Steven Hebert, Tong Wang
Source: American journal of physiology. Regulatory, integrative and comparative physiology. 2008 Sep
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