1 to 10 of 16 literature results

• Graph-based semisupervised learning.

  Graph-based learning provides a useful approach for modeling data in classification problems. In this modeling scenario, the relationship between labe…

  Authors: Mark Culp, George Michailidis

  Source: IEEE transactions on pattern analysis and machine intelligence. 2008 Jan

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• Quantitative organellar proteomics analysis of rough endoplasmic reticulum from normal and acute pancreatitis rat pancreas.

  The rough endoplasmic reticulum (RER) is a central organelle for synthesizing and processing digestive enzymes and alteration of ER functions may part…

  Authors: Xuequn Chen, Maria Dolors Sans, John R Strahler, Alla Karnovsky, Stephen A Ernst, George Michailidis, Philip C Andrews, John A Williams

  Source: Journal of proteome research. 2010 Feb 5

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• Temporal quantitative proteomics by iTRAQ 2D-LC-MS/MS and corresponding mRNA expression analysis identify post-transcriptional modulation of actin-cytoskeleton regulators during TGF-beta-Induced epithelial-mesenchymal transition.

  To gain insights into how TGF-beta regulates epithelial-mesenchymal transition (EMT), we assessed the time course of proteins and mRNAs during EMT by …

  Authors: Venkateshwar G Keshamouni, Pratik Jagtap, George Michailidis, John R Strahler, Rork Kuick, Ajaya Kumar Reka, Panagiotis Papoulias, Rashmi Krishnapuram, Anjaiah Srirangam, Theodore J Standiford,…

  Source: Journal of proteome research. 2009 Jan

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• Early events of Bacillus anthracis germination identified by time-course quantitative proteomics.

  Germination of Bacillus anthracis spores involves rehydration of the spore interior and rapid degradation of several of the protective layers, includi…

  Authors: Pratik Jagtap, George Michailidis, Ryszard Zielke, Angela K Walker, Nishi Patel, John R Strahler, Adam Driks, Philip C Andrews, Janine R Maddock

  Source: Proteomics. 2006 Oct

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• Differential protein expression profiling by iTRAQ-2DLC-MS/MS of lung cancer cells undergoing epithelial-mesenchymal transition reveals a migratory/invasive phenotype.

  Transforming growth factor-beta (TGF-beta) induces epithelial-mesenchymal transition (EMT) of epithelial cells in both normal embryonic development an…

  Authors: Venkateshwar G Keshamouni, George Michailidis, Catherine S Grasso, Shalini Anthwal, John R Strahler, Angela Walker, Douglas A Arenberg, Raju C Reddy, Sudhakar Akulapalli, Victor J Thannickal,…

  Source: Journal of proteome research. 2006 May

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• Immunoassay and antibody microarray analysis of the HUPO Plasma Proteome Project reference specimens: systematic variation between sample types and calibration of mass spectrometry data.

  Four different immunoassay and antibody microarray methods performed at four different sites were used to measure the levels of a broad range of prote…

  Authors: Brian B Haab, Bernhard H Geierstanger, George Michailidis, Frank Vitzthum, Sara Forrester, Ryan Okon, Petri Saviranta, Achim Brinker, Martin Sorette, Lorah Perlee,…

  Source: Proteomics. 2005 Aug

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• Development of natural protein microarrays for diagnosing cancer based on an antibody response to tumor antigens.

  The detection of autoantibodies to tumor antigens has potential utility for the early diagnosis of cancers. In previous studies, we have identified tu…

  Authors: Ji Qiu, Juan Madoz-Gurpide, David E Misek, Rork Kuick, Dean E Brenner, George Michailidis, Brian B Haab, Gilbert S Omenn, Sam Hanash

  Source: Journal of proteome research. 2004 Mar-Apr

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• Analysis of gene sets based on the underlying regulatory network.

  Networks are often used to represent the interactions among genes and proteins. These interactions are known to play an important role in vital cell f…

  Authors: Ali Shojaie, George Michailidis

  Source: Journal of computational biology : a journal of computational molecular cell biology. 2009 Mar

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• Gene expression in ovarian cancer reflects both morphology and biological behavior, distinguishing clear cell from other poor-prognosis ovarian carcinomas.

  Biologically and clinically meaningful tumor classification schemes have long been sought. Some malignant epithelial neoplasms, such as those in the t…

  Authors: Donald R Schwartz, Sharon L R Kardia, Kerby A Shedden, Rork Kuick, George Michailidis, Jeremy M G Taylor, David E Misek, Rong Wu, Yali Zhai, Danielle M Darrah,…

  Source: Cancer research. 2002 Aug 15

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• The ensemble bridge algorithm: a new modeling tool for drug discovery problems.

  Ensemble algorithms have been historically categorized into two separate paradigms, boosting and random forests, which differ significantly in the way…

  Authors: Mark Culp, Kjell Johnson, George Michailidis

  Source: Journal of chemical information and modeling. 2010 Feb 22

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