1 to 7 of 7 literature results

• Corequirement of PICK1 binding and PKC phosphorylation for stable surface expression of the metabotropic glutamate receptor mGluR7.

  The presynaptic metabotropic glutamate receptor (mGluR) mGluR7 modulates excitatory neurotransmission by regulating neurotransmitter release and plays…

  Authors: Young Ho Suh, Kenneth A Pelkey, Gabriela Lavezzari, Paul A Roche, Richard L Huganir, Chris J McBain, Katherine W Roche

  Source: Neuron. 2008 Jun 12

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• mGluR7 is a metaplastic switch controlling bidirectional plasticity of feedforward inhibition.

  Plasticity of feedforward inhibition in the hippocampal mossy fiber (MF) pathway can dramatically influence dentate gyrus-CA3 dialog. Interestingly, M…

  Authors: Kenneth A Pelkey, Gabriela Lavezzari, Claudia Racca, Katherine W Roche, Chris J McBain

  Source: Neuron. 2005 Apr 7

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• Constitutive endocytosis of the metabotropic glutamate receptor mGluR7 is clathrin-independent.

  Metabotropic glutamate receptors (mGluRs) are G protein-coupled receptors (GPCRs) that are widely expressed throughout the brain and are involved in s…

  Authors: Gabriela Lavezzari, Katherine W Roche

  Source: Neuropharmacology. 2007 Jan

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• mGluR7 undergoes rapid internalization in response to activation by the allosteric agonist AMN082.

  The G-protein coupled receptor (GPCR) metabotropic glutamate receptor 7 (mGluR7) is widely expressed throughout the nervous system and is implicated i…

  Authors: Kenneth A Pelkey, Xiaoqing Yuan, Gabriela Lavezzari, Katherine W Roche, Chris J McBain

  Source: Neuropharmacology. 2007 Jan

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• Differential binding of the AP-2 adaptor complex and PSD-95 to the C-terminus of the NMDA receptor subunit NR2B regulates surface expression.

  NMDA receptor expression on the plasma membrane and at synaptic sites is tightly regulated. We have recently shown that the NMDA receptor subunit NR2B…

  Authors: Gabriela Lavezzari, Jennifer McCallum, Robert Lee, Katherine W Roche

  Source: Neuropharmacology. 2003 Nov

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• Inhibition of transforming growth factor beta receptor I kinase blocks hepatocellular carcinoma growth through neo-angiogenesis regulation.

  Curative therapies for patients with hepatocellular carcinoma (HCC) are mainly invasive, and with the exception of sorafenib, no medical treatments ar…

  Authors: Antonio Mazzocca, Emilia Fransvea, Gabriela Lavezzari, Salvatore Antonaci, Gianluigi Giannelli

  Source: Hepatology (Baltimore, Md.). 2009 Oct

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• Subunit-specific regulation of NMDA receptor endocytosis.

  At excitatory synapses, both NMDA and AMPA receptors are localized to the postsynaptic density (PSD). However, unlike AMPA receptors, synaptic NMDA re…

  Authors: Gabriela Lavezzari, Jennifer McCallum, Colleen M Dewey, Katherine W Roche

  Source: The Journal of neuroscience : the official journal of the Society for Neuroscience. 2004 Jul 14

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