10 literature results

• Sweet talk": closing in on C type lectin signaling.

  C type lectins recognize pathogens by binding to pathogen-specific carbohydrate residues. The finding reported by Rogers et al. (2005) in this issue o…

  Authors: Friederike Meyer-Wentrup, Alessandra Cambi, Gosse J Adema, Carl G Figdor

  Source: Immunity. 2005 Apr

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• Targeting DCIR on human plasmacytoid dendritic cells results in antigen presentation and inhibits IFN-alpha production.

  C-type lectin receptors (CLRs) fulfill multiple functions within the immune system by recognition of carbohydrate moieties on foreign or (altered) sel…

  Authors: Friederike Meyer-Wentrup, Daniel Benitez-Ribas, Paul J Tacken, Cornelis J A Punt, Carl G Figdor, I Jolanda M de Vries, Gosse J Adema

  Source: Blood. 2008 Apr 15

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• Dectin-1 synergizes with TLR2 and TLR4 for cytokine production in human primary monocytes and macrophages.

  The beta-glucan receptor dectin-1 and Toll-like receptors TLR2 and TLR4 are the main receptors for recognition of Candida albicans by the innate immun…

  Authors: Gerben Ferwerda, Friederike Meyer-Wentrup, Bart-Jan Kullberg, Mihai G Netea, Gosse J Adema

  Source: Cellular microbiology. 2008 Oct

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• DCIR is endocytosed into human dendritic cells and inhibits TLR8-mediated cytokine production.

  C-type lectin receptors (CLRs) expressed on APCs play a pivotal role in the immune system as pattern-recognition and antigen-uptake receptors. In addi…

  Authors: Friederike Meyer-Wentrup, Alessandra Cambi, Ben Joosten, Maaike W Looman, I Jolanda M de Vries, Carl G Figdor, Gosse J Adema

  Source: Journal of leukocyte biology. 2009 Mar

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• Syk kinase is required for collaborative cytokine production induced through Dectin-1 and Toll-like receptors.

  Recognition of microbial components by germ-line encoded pattern recognition receptors (PRR) initiates immune responses to infectious agents. We and o…

  Authors: Kevin M Dennehy, Gerben Ferwerda, Inês Faro-Trindade, Elwira Pyz, Janet A Willment, Philip R Taylor, Ann Kerrigan, S Vicky Tsoni, Siamon Gordon, Friederike Meyer-Wentrup,…

  Source: European journal of immunology. 2008 Feb

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• Circulating CXCL16 is not related to circulating oxLDL in patients with rheumatoid arthritis.

  CXCL16 acts as a scavenger receptor for oxLDL in its membrane-bound form and induces migration of activated T cells in its soluble form. Due to these …

  Authors: Antoine W T van Lieshout, Calin Popa, Friederike Meyer-Wentrup, Heidi L Lemmers, Anton F Stalenhoef, Gosse J Adema, Piet L C M van Riel, Lambertus J van Tits, Timothy R D J Radstake

  Source: Biochemical and biophysical research communications. 2007 Apr 6

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• Efficacy of dendritic cell generation for clinical use: recovery and purity of monocytes and mature dendritic cells after immunomagnetic sorting or adherence selection of CD14+ starting populations.

  Immunotherapy with monocyte-derived dendritic cells (Mo-DCs) is applied to an increasing number of patients requiring large-scale production of clinic…

  Authors: Friederike Meyer-Wentrup, Stefan Burdach

  Source: Journal of hematotherapy & stem cell research. 2003 Jun

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• Identification of an immunogenic EWS-FLI1-derived HLA-DR-restricted T helper cell epitope.

  Immunotherapy with tumor-specific peptide-loaded dendritic cells represents a promising therapeutic approach for patients with multifocal primary or e…

  Authors: Friederike Meyer-Wentrup, Günther Richter, Stefan Burdach

  Source: Pediatric hematology and oncology. 2005 Jun

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• Dectin-1 interaction with tetraspanin CD37 inhibits IL-6 production.

  C-type lectins are pattern-recognition receptors important for pathogen binding and uptake by APCs. Evidence is accumulating that integration of incom…

  Authors: Friederike Meyer-Wentrup, Carl G Figdor, Marleen Ansems, Peter Brossart, Mark D Wright, Gosse J Adema, Annemiek B van Spriel

  Source: Journal of immunology (Baltimore, Md. : 1950). 2007 Jan 1

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• The inhibitory Fc gamma IIb receptor dampens TLR4-mediated immune responses and is selectively up-regulated on dendritic cells from rheumatoid arthritis patients with quiescent disease.

  Rheumatoid arthritis (RA) is a common autoimmune disease leading to profound disability and premature death. Although a role for FcgammaRs and TLRs is…

  Authors: Mark H Wenink, Kim C M Santegoets, Mieke F Roelofs, Richard Huijbens, Hans J P M Koenen, Ronald van Beek, Irma Joosten, Friederike Meyer-Wentrup, Linda Mathsson, Johan Ronnelid,…

  Source: Journal of immunology (Baltimore, Md. : 1950). 2009 Oct 1

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