1 to 10 of 166 literature results

• A role for adult TLX-positive neural stem cells in learning and behaviour.

  Neurogenesis persists in the adult brain and can be regulated by a plethora of external stimuli, such as learning, memory, exercise, environment and s…

  Authors: Chun-Li Zhang, Yuhua Zou, Weimin He, Fred H Gage, Ronald M Evans

  Source: Nature. 2008 Feb 21

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• Generation of neuronal variability and complexity.

  The production of specialized differentiated neurons derived from stem cells has been proposed as a revolutionary technology for regenerative medicine…

  Authors: Alysson R Muotri, Fred H Gage

  Source: Nature. 2006 Jun 29

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• Development of a novel mouse glioma model using lentiviral vectors.

  We report the development of a new method to induce glioblastoma multiforme in adult immunocompetent mice by injecting Cre-loxP-controlled lentiviral …

  Authors: Tomotoshi Marumoto, Ayumu Tashiro, Dinorah Friedmann-Morvinski, Miriam Scadeng, Yasushi Soda, Fred H Gage, Inder M Verma

  Source: Nature medicine. 2009 Jan

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• Signaling in adult neurogenesis.

  The identification of neural stem cells (NSCs) and their contribution to continuous neurogenesis has shown that the hippocampus and olfactory bulb are…

  Authors: Hoonkyo Suh, Wei Deng, Fred H Gage

  Source: Annual review of cell and developmental biology. 2009

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• Mechanisms and functional implications of adult neurogenesis.

  The generation of new neurons is sustained throughout adulthood in the mammalian brain due to the proliferation and differentiation of adult neural st…

  Authors: Chunmei Zhao, Wei Deng, Fred H Gage

  Source: Cell. 2008 Feb 22

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• L1 retrotransposition in human neural progenitor cells.

  Long interspersed element 1 (LINE-1 or L1) retrotransposons have markedly affected the human genome. L1s must retrotranspose in the germ line or durin…

  Authors: Nicole G Coufal, José L Garcia-Perez, Grace E Peng, Gene W Yeo, Yangling Mu, Michael T Lovci, Maria Morell, K Sue O'Shea, John V Moran, Fred H Gage

  Source: Nature. 2009 Aug 27

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• A Nurr1/CoREST pathway in microglia and astrocytes protects dopaminergic neurons from inflammation-induced death.

  Nurr1, an orphan nuclear receptor, plays an essential role in the generation and maintenance of dopaminergic neurons in the brain. Rare mutations in N…

  Authors: Kaoru Saijo, Beate Winner, Christian T Carson, Jana G Collier, Leah Boyer, Michael G Rosenfeld, Fred H Gage, Christopher K Glass

  Source: Cell. 2009 Apr 3

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• Fate plasticity of adult hippocampal progenitors: biological relevance and therapeutic use.

  Adult hippocampal stem/progenitor cells (AHPs) continuously give rise to new neurons throughout life, which might be an important determinant of hippo…

  Authors: Sebastian Jessberger, Fred H Gage

  Source: Trends in pharmacological sciences. 2009 Feb

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• Computational influence of adult neurogenesis on memory encoding.

  Adult neurogenesis in the hippocampus leads to the incorporation of thousands of new granule cells into the dentate gyrus every month, but its functio…

  Authors: James B Aimone, Janet Wiles, Fred H Gage

  Source: Neuron. 2009 Jan 29

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• Noncoding RNAs in the mammalian central nervous system.

  The central nervous system (CNS) is arguably one of the most complex systems in the universe. To understand the CNS, scientists have investigated a va…

  Authors: Xinwei Cao, Gene Yeo, Alysson R Muotri, Tomoko Kuwabara, Fred H Gage

  Source: Annual review of neuroscience. 2006

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