1 to 6 of 6 literature results

• Syndecan-4 regulates ADAMTS-5 activation and cartilage breakdown in osteoarthritis.

  Aggrecan cleavage by a disintegrin and metalloproteinase with a thrombospondin type 1 motif, member 5 (ADAMTS-5) is crucial for the breakdown of carti…

  Authors: Frank Echtermeyer, Jessica Bertrand, Rita Dreier, Ingmar Meinecke, Katja Neugebauer, Martin Fuerst, Yun Jong Lee, Yeong Wook Song, Christine Herzog, Gregor Theilmeier,…

  Source: Nature medicine. 2009 Sep

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• Lidocaine protects from myocardial damage due to ischemia and reperfusion in mice by its antiapoptotic effects.

  BACKGROUND: Perioperative myocardial ischemia poses a vital threat to surgical patients. Means to protect postischemic myocardium are clinically not a…

  Authors: Dominik J Kaczmarek, Christine Herzog, Jan Larmann, Hans-Jörg Gillmann, Reinhard Hildebrand, Martina Schmitz, Anik Westermann, Thomas Harendza, Robert Werdehausen, Alexander W Osthaus,…

  Source: Anesthesiology. 2009 May

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• Expression of transcription factors and matrix genes in response to serum stimulus in vascular smooth muscle cells.

  During atherogenesis vascular smooth muscle cells are converted from a contractile into a synthetic phenotype characterized by enhanced matrix product…

  Authors: André Markmann, Jürgen Rauterberg, Peter Vischer, Horst Robenek, Frank Echtermeyer, Heike Will, Daniela G Seidler, Marian F Young, Hans Kresse

  Source: European journal of cell biology. 2003 Mar

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• Unilateral nephrectomy leads to up-regulation of syndecan-2- and TGF-beta-mediated glomerulosclerosis in syndecan-4 deficient male mice.

  Syndecan-4 is an ubiquitous, plasma membrane-spanning heparan sulfate proteoglycan involved in proliferation, differentiation, adhesion and migration …

  Authors: Ferda Cevikbas, Liliana Schaefer, Philipp Uhlig, Horst Robenek, Gregor Theilmeier, Frank Echtermeyer, Peter Bruckner

  Source: Matrix biology : journal of the International Society for Matrix Biology. 2008 Jan

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• Plasmin- and thrombin-accelerated shedding of syndecan-4 ectodomain generates cleavage sites at Lys(114)-Arg(115) and Lys(129)-Val(130) bonds.

  Syndecans are transmembranous heparan sulfate proteoglycans abundant in the surface of all adherent mammalian cells and involved in vital cellular fun…

  Authors: Annette Schmidt, Frank Echtermeyer, Anthony Alozie, Kerstin Brands, Eckhart Buddecke

  Source: The Journal of biological chemistry. 2005 Oct 14

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• Syndecan-1 as a regulator of chemokine function.

  Authors: Martin Götte, Frank Echtermeyer

  Source: TheScientificWorldJournal. 2003 Dec 11

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