1 to 9 of 9 literature results

• p38{gamma} regulates interaction of nuclear PSF and RNA with the tumour-suppressor hDlg in response to osmotic shock.

  Activation of p38gamma modulates the integrity of the complex formed by the human discs large protein (hDlg) with cytoskeletal proteins, which is impo…

  Authors: Guadalupe Sabio, María I Cerezo-Guisado, Paloma Del Reino, Francisco A Iñesta-Vaquera, Simon Rousseau, J Simon C Arthur, David G Campbell, Francisco Centeno, Ana Cuenda

  Source: Journal of cell science. 2010 Jul 6

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• Lithium blocks the PKB and GSK3 dephosphorylation induced by ceramide through protein phosphatase-2A.

  The biochemical mechanism of apoptosis induced by ceramide remains still unclear, although it has been reported that dephosphorylation of PKB at Ser-4…

  Authors: Alfonso Mora, Guadalupe Sabio, Ana María Risco, Ana Cuenda, Juan C Alonso, Germán Soler, Francisco Centeno

  Source: Cellular signalling. 2002 Jun

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• Different dependence of lithium and valproate on PI3K/PKB pathway.

  OBJECTIVES: Acute treatment with valproate (VPA) or lithium (Li+) protects cerebellar granule cells (CGC) against apoptosis induced by low potassium (…

  Authors: Alfonso Mora, Guadalupe Sabio, Juan C Alonso, Germán Soler, Francisco Centeno

  Source: Bipolar disorders. 2002 Jun

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• Proteolysis of the tumour suppressor hDlg in response to osmotic stress is mediated by caspases and independent of phosphorylation.

  Human disc-large (hDlg) is a scaffold protein critical for the maintenance of cell polarity and adhesion. hDlg is a component of the p38gamma MAP kina…

  Authors: Francisco A Iñesta-Vaquera, Francisco Centeno, Paloma del Reino, Guadalupe Sabio, Mark Peggie, Ana Cuenda

  Source: The FEBS journal. 2009 Jan

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• SDS-PAGE and Western blot of urinary proteins in dogs with leishmaniasis.

  Canine leishmaniasis is an endemic disease in the Mediterranean area caused by the protozoan Leishmania infantum, which usually produces renal failure…

  Authors: Concepción Zaragoza, Rafael Barrera, Francisco Centeno, Jose A Tapia, Esther Durán, Marta González, M Cinta Mañé

  Source: Veterinary research. 2003 Mar-Apr

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• Crystal structure of human arginase I at 1.29-A resolution and exploration of inhibition in the immune response.

  Human arginase I is a potential target for therapeutic intervention in diseases linked to compromised l-arginine homeostasis. Here, we report high-aff…

  Authors: Luigi Di Costanzo, Guadalupe Sabio, Alfonso Mora, Paulo C Rodriguez, Augusto C Ochoa, Francisco Centeno, David W Christianson

  Source: Proceedings of the National Academy of Sciences of the United States of America. 2005 Sep 13

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• p38gamma regulates the localisation of SAP97 in the cytoskeleton by modulating its interaction with GKAP.

  Activation of the p38 MAP kinase pathways is crucial for the adaptation of mammalian cells to changes in the osmolarity of the environment. Here we id…

  Authors: Guadalupe Sabio, James Simon Campbell Arthur, Yvonne Kuma, Mark Peggie, Julia Carr, Vicky Murray-Tait, Francisco Centeno, Michel Goedert, Nicholas A Morrice, Ana Cuenda

  Source: The EMBO journal. 2005 Mar 23

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• Resveratrol-induced apoptosis in MCF-7 human breast cancer cells involves a caspase-independent mechanism with downregulation of Bcl-2 and NF-kappaB.

  Resveratrol (RES), a chemopreventive molecule, inhibits the proliferation of tumor cells of different etiologies. We previously showed that RES alters…

  Authors: Eulalia Pozo-Guisado, Jaime M Merino, Sonia Mulero-Navarro, M Jesús Lorenzo-Benayas, Francisco Centeno, Alberto Alvarez-Barrientos, Pedro M Fernandez-Salguero, Pedro M Fernandez Salguero

  Source: International journal of cancer. Journal international du cancer. 2005 May 20

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• Stress- and mitogen-induced phosphorylation of the synapse-associated protein SAP90/PSD-95 by activation of SAPK3/p38gamma and ERK1/ERK2.

  SAPK3 (stress-activated protein kinase-3, also known as p38gamma) is a member of the mitogen-activated protein kinase family; it phosphorylates substr…

  Authors: Guadalupe Sabio, Suzana Reuver, Carmen Feijoo, Masato Hasegawa, Gareth M Thomas, Francisco Centeno, Sven Kuhlendahl, Sergio Leal-Ortiz, Michel Goedert, Craig Garner,…

  Source: The Biochemical journal. 2004 May 15

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