1 to 10 of 79 literature results

• Defective tryptophan catabolism underlies inflammation in mouse chronic granulomatous disease.

  Half a century ago, chronic granulomatous disease (CGD) was first described as a disease fatally affecting the ability of children to survive infectio…

  Authors: Luigina Romani, Francesca Fallarino, Antonella De Luca, Claudia Montagnoli, Carmen D'Angelo, Teresa Zelante, Carmine Vacca, Francesco Bistoni, Maria C Fioretti, Ursula Grohmann,…

  Source: Nature. 2008 Jan 10

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• Reverse signaling through GITR ligand enables dexamethasone to activate IDO in allergy.

  Glucocorticoid-induced tumor necrosis factor receptor (GITR) on T cells and its natural ligand, GITRL, on accessory cells contribute to the control of…

  Authors: Ursula Grohmann, Claudia Volpi, Francesca Fallarino, Silvia Bozza, Roberta Bianchi, Carmine Vacca, Ciriana Orabona, Maria L Belladonna, Emira Ayroldi, Giuseppe Nocentini,…

  Source: Nature medicine. 2007 May

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• Thymosin alpha1 activates dendritic cell tryptophan catabolism and establishes a regulatory environment for balance of inflammation and tolerance.

  Thymosin alpha1 (Talpha1), a naturally occurring thymic peptide, primes dendritic cells (DCs) for antifungal T-helper type 1 resistance through Toll-l…

  Authors: Luigina Romani, Francesco Bistoni, Katia Perruccio, Claudia Montagnoli, Roberta Gaziano, Silvia Bozza, Pierluigi Bonifazi, Giovanni Bistoni, Guido Rasi, Andrea Velardi,…

  Source: Blood. 2006 Oct 1

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• Capsular polysaccharide induction of apoptosis by intrinsic and extrinsic mechanisms.

  A purified microbial capsular polysaccharide of Cryptococcus neoformans, glucuronoxylomannan (GXM), induces Fas ligand (FasL) upregulation on macropha…

  Authors: Claudia Monari, Francesca Paganelli, Francesco Bistoni, Thomas R Kozel, Anna Vecchiarelli

  Source: Cellular microbiology. 2008 Oct

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• Toll-like receptor 2 deficiency is associated with enhanced severity of group B streptococcal disease.

  Group B streptococcus (GBS) has been recognized as an ever-growing cause of serious invasive infections in nonpregnant adults, in particular, in assoc…

  Authors: Manuela Puliti, Satoshi Uematsu, Shizuo Akira, Francesco Bistoni, Luciana Tissi

  Source: Infection and immunity. 2009 Apr

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• Indinavir influences biological function of dendritic cells and stimulates antifungal immunity.

  In this study, we analyzed the possibility that Indinavir (IDV), a well-known protease inhibitor (PI) used in highly active antiretroviral therapy, co…

  Authors: Eva Pericolini, Elio Cenci, Elena Gabrielli, Stefano Perito, Paolo Mosci, Francesco Bistoni, Anna Vecchiarelli

  Source: Journal of leukocyte biology. 2008 May

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• Polymorphisms in Toll-like receptor genes and susceptibility to infections in allogeneic stem cell transplantation.

  OBJECTIVE: Discovery of genetic variations in the genes encoding for Toll-like receptors (TLRs) has highlighted a potential link between genomic varia…

  Authors: Agostinho Carvalho, Cristina Cunha, Alessandra Carotti, Teresa Aloisi, Ornella Guarrera, Mauro Di Ianni, Franca Falzetti, Francesco Bistoni, Franco Aversa, Lucia Pitzurra,…

  Source: Experimental hematology. 2009 Sep

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• Pentraxin 3 protects from MCMV infection and reactivation through TLR sensing pathways leading to IRF3 activation.

  Reactivation of latent human cytomegalovirus (HCMV) following allogeneic transplantation is a major cause of morbidity and mortality and predisposes t…

  Authors: Silvia Bozza, Francesco Bistoni, Roberta Gaziano, Lucia Pitzurra, Teresa Zelante, Pierluigi Bonifazi, Katia Perruccio, Silvia Bellocchio, Mariella Neri, Anna Maria Iorio,…

  Source: Blood. 2006 Nov 15

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• Adaptation of Candida albicans to the host environment: the role of morphogenesis in virulence and survival in mammalian hosts.

  Although morphological flexibility could be a key contributor to fungal virulence, no molecular data has unambiguously established fungal morphogenesi…

  Authors: Luigina Romani, Francesco Bistoni, Paolo Puccetti

  Source: Current opinion in microbiology. 2003 Aug

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• A Candida albicans mannoprotein deprived of its mannan moiety is efficiently taken up and processed by human dendritic cells and induces T-cell activation without stimulating proinflammatory cytokine production.

  Mannoproteins are cell wall components of pathogenic fungi and play major virulence and immunogenic roles with both their mannan and protein moieties.…

  Authors: Donatella Pietrella, Patrizia Lupo, Anna Rachini, Silvia Sandini, Alessandra Ciervo, Stefano Perito, Francesco Bistoni, Anna Vecchiarelli

  Source: Infection and immunity. 2008 Sep

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