1 to 7 of 7 literature results

• Recombinant factor VIIa partially reverses the inhibitory effect of fondaparinux on thrombin generation after tissue factor activation in platelet rich plasma and whole blood.

  Fondaparinux (Arixtra), a specific AT-dependent FXa inhibitor, is effective and safe in the prevention and treatment of venous thromboembolism, but so…

  Authors: Grigoris T Gerotziafas, François Depasse, Tahar Chakroun, Meyer M Samama, Ismail Elalamy

  Source: Thrombosis and haemostasis. 2004 Mar

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• The role of platelets and recombinant factor VIIa on thrombin generation, platelet activation and clot formation.

  In the present study we assessed the effect of platelet counts and rFVIIa on thrombin generation, platelet activation and clot formation after tissue …

  Authors: Grigoris T Gerotziafas, Tahar Chakroun, François Depasse, Pantelis Arzoglou, Meyer M Samama, Ismail Elalamy

  Source: Thrombosis and haemostasis. 2004 May

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• Proteomics of methylene blue photo-treated plasma before and after removal of the dye by an absorbent filter.

  Methylene blue (MB) and light are used for virus inactivation of plasma for transfusion. However, the presence of MB has been the subject of concern, …

  Authors: David Crettaz, Luc Sensebe, Dinh-Hao Vu, Philippe Schneider, François Depasse, Willy-Vincent Bienvenut, Manfredo Quadroni, Jean-Daniel Tissot

  Source: Proteomics. 2004 Mar

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• The influence of methylene blue light treatment and methylene blue removal filter on fibrinogen activity states and fibrin polymerisation indices.

  BACKGROUND-OBJECTIVE: Methylene blue light treatment (MBLT) is efficient in inactivating viruses in plasma. However, it may cause alterations in clott…

  Authors: François Depasse, Luc Sensebé, Jerard Seghatchian, Georges Andreu, Meyer-Michel Samama

  Source: Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis. 2005 Aug

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• Towards a standardization of thrombin generation assessment: the influence of tissue factor, platelets and phospholipids concentration on the normal values of Thrombogram-Thrombinoscope assay.

  BACKGROUND: Thrombin generation assay was developed several years ago to mimic physiological coagulation mechanisms but it had important limitations. …

  Authors: Grigoris T Gerotziafas, François Depasse, Joël Busson, Lena Leflem, Ismail Elalamy, Meyer M Samama

  Source: Thrombosis journal. 2005 Oct 26

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• Comparison of the effect of fondaparinux and enoxaparin on thrombin generation during in-vitro clotting of whole blood and platelet-rich plasma.

  Fondaparinux, a selective antithrombin-dependent inhibitor of activated factor X (FXa), is effective in the prevention and treatment of deep vein thro…

  Authors: Grigoris T Gerotziafas, François Depasse, Tahar Chakroun, Patrick Van Dreden, Meyer M Samama, Ismail Elalamy

  Source: Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis. 2004 Mar

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• On the mechanism of inhibition of tissue factor pathway by the synthetic pentasaccharide during coagulation of human plasma.

  The tissue factor (TF) pathway is preponderant in the initiation of blood coagulation in normal haemostasis and in thrombotic states. In the present s…

  Authors: Grigoris T Gerotziafas, Ismail Elalamy, François Depasse, Tahar Chakroun, Lucienne Bara, Pantelis Arzoglou, Meyer M Samama

  Source: Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis. 2003 Oct

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