1 to 10 of 17 literature results

• Hemoglobin binding to A beta and HBG2 SNP association suggest a role in Alzheimer's disease.

  From a normal human brain phage display library screen we identified the gamma (A)-globin chain of fetal hemoglobin (Hb F) as a protein that bound str…

  Authors: Rodney T Perry, Debra A Gearhart, Howard W Wiener, Lindy E Harrell, James C Barton, Abdullah Kutlar, Ferdane Kutlar, Ozan Ozcan, Rodney C P Go, William D Hill

  Source: Neurobiology of aging. 2008 Feb

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• Missense mutation of the last nucleotide of exon 1 (G->C) of beta globin gene not only leads to undetectable mutant peptide and transcript but also interferes with the expression of wild allele.

  Hemoglobin Monroe (beta globin G->C, codon 30) is a missense mutation. We could not detect either the mutant peptide or transcript in reticulocyte-enr…

  Authors: Neeraj Agarwal, Ferdane Kutlar, Mariluz P Mojica-Henshaw, Ching N Ou, Amos Gaikwad, N Scott Reading, Lakeia Bailey, Abdullah Kutlar, Josef T Prchal

  Source: Haematologica. 2007 Dec

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• Acute splenic complications and implications of splenectomy in hemoglobin SC disease.

  Splenectomy indications and outcome were evaluated in 124 adults with hemoglobin SC disease (Hb SC). Twelve patients (9.6%) required splenectomy. Ther…

  Authors: Karthi Subbannan, Celalettin Ustun, Kavita Natarajan, Betsy Clair, Lisa Daitch, Sabine Fields, Ferdane Kutlar, Abdullah Kutlar

  Source: European journal of haematology. 2009 Sep

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• Rare occurrence of Hb Lepore-Baltimore in African Americans: molecular characteristics and variations of Hb Lepores.

  Hb Lepore is the hybrid hemoglobin (Hb) composed of two alpha-globin chains and two deltabeta hybrid chains and is associated with the clinical findin…

  Authors: Sean M McKeown, Harris Carmichael, Rhea-Beth Markowitz, Abdullah Kutlar, Leslie Holley, Ferdane Kutlar

  Source: Annals of hematology. 2009 Jun

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• Diagnostic approach to hemoglobinopathies.

  Abnormalities of hemoglobin (Hb) synthesis are among the most common inherited disorders of man and can be quantitative (thalassemia syndromes) or qua…

  Authors: Ferdane Kutlar

  Source: Hemoglobin. 2007

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• Two new hemoglobin variants: Hb Sinai-Greenspring [beta34(B16)Val-->Ile, GTC > ATC] and Hb Sinai-Bel Air [beta53(D4)Ala-->Asp, GCT > GAT].

  Neonatal screening for hemoglobinopathies occasionally results in the detection of novel hemoglobin (Hb) variants. Two heterozygous infants were found…

  Authors: Erin Dainer, Robert E Wenk, Ruth Luddy, Dedrey Elam, Leslie Holley, Abdullah Kutlar, Ferdane Kutlar

  Source: Hemoglobin. 2008

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• Interaction of sickle cell trait with hereditary spherocytosis: splenic infarcts and sequestration.

  The association of sickle cell trait (SCT) and hereditary spherocytosis (HS) has been reported in only 18 patients. Three of these 18 patients experie…

  Authors: Celatettin Ustun, Ferdane Kutlar, Leslie Holley, Maree Seigler, Russell Burgess, Abdullah Kutlar

  Source: Acta haematologica. 2003

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• Neonatal cyanosis due to a novel fetal hemoglobin: Hb F-Circleville [Ggamma63(E7)His-->Leu, CAT>CTT].

  Neonatal cyanosis can result from a multitude of acquired and inherited causes. Cyanosis resulting from fetal M hemoglobin (Hb) variants is very rare.…

  Authors: Erin Dainer, Richard Shell, Randy Miller, Joan F Atkin, Matt Pastore, Abdullah Kutlar, Lina Zhuang, Leslie Holley, Debra H Davis, Ferdane Kutlar

  Source: Hemoglobin. 2008

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• Aplastic crisis revealing the diagnosis of Hb Evans [alpha62(E11)Val-->Met, GTG-->ATG (alpha2)] in a Hispanic kindred: case report and review.

  This report describes a Hispanic girl who presented in aplastic crisis due to parvovirus infection. She was subsequently found to have a chronic hemol…

  Authors: Laurie A Steiner, Jack Van Hoff, Ferdane Kutlar, Patrick G Gallagher

  Source: Hemoglobin. 2007

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• Compound heterozygosity for hemoglobin S [beta6(A3)Glu6Val] and hemoglobin Korle-Bu [beta73(E17)Asp73Asn].

  We report a case of compound heterozygous hemoglobins S [beta6(A3)Glu6Val] and Korle-Bu [beta73(E17)Asp73Asn] in a 2-year-old girl. This hemoglobin ge…

  Authors: Pascale S Akl, Ferdane Kutlar, Niren Patel, Catherine L Salisbury, Peter Lane, Andrew N Young

  Source: Laboratory hematology : official publication of the International Society for Laboratory Hematology. 2009

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